Protein Alignment Cdk2 and MAK

DIOPT Version :10

• Sequence 1: NP_524420.1
• Gene: Cdk2 / 42453
• FlyBaseID: FBgn0004107
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: NP_001229886.1
• Gene: MAK / 4117
• HGNCID: 6816
• Length: 648
• Species: Homo sapiens
• Alignment Length: 291
• Identity: 110/291 - (37%)
• Similarity: 175/291 - (60%)
• Gaps: 13/291 - (4%)

  Fly     5 LDNFQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLE----GETEGVPSTAIREISLLKNLKHP 65
            ::.:....::|:||||.|...:||.:|:.||:|:::.:    .|...     :||:..||.|.|.
Human     1 MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMN-----LREVKSLKKLNHA 60

  Fly    66 NVVQLFDVVISGNNLYMIFEYLNMDLKKLMDKKKDVFTPQLIKSYMHQILDAVGFCHTNRILHRD 130
            ||::|.:|:...::||.||||:..:|.:||..:..:|...:|::.|:|||..:.|.|.:...|||
Human    61 NVIKLKEVIRENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHGFFHRD 125

  Fly   131 LKPQNLLVDTAGKIKLADFGLARAFNVPMRAYTHEVVTLWYRAPEILLGTKFYSTGVDIWSLGCI 195
            :||:|||......:|:|||||||... ....||..|.|.||||||:||.:..||:.:|:|::|.|
Human   126 MKPENLLCMGPELVKIADFGLARELR-SQPPYTDYVSTRWYRAPEVLLRSSVYSSPIDVWAVGSI 189

  Fly   196 FSEMIMRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQL-PDFKTKFPRWEGTNMPQ--PITE 257
            .:|:.|.|.||||.||:|::::|.:.|.||.:::||...|| .....:||:....|:..  |...
Human   190 MAELYMLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQCVPINLKTLIPNAS 254

  Fly   258 HEAHELIMSMLCYDPNLRISAKDALQHAYFR 288
            :||.:|:..||.:||..|.:|..||:|.||:
Human   255 NEAIQLMTEMLNWDPKKRPTASQALKHPYFQ 285

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk2	NP_524420.1	STKc_CDK1_CdkB_like	8..287	CDD:270829	108/285 (38%)
MAK	NP_001229886.1	STKc_MAK_like	4..284	CDD:270824	108/285 (38%)