Protein Alignment Cdk2 and mapk3

DIOPT Version :10

• Sequence 1: NP_524420.1
• Gene: Cdk2 / 42453
• FlyBaseID: FBgn0004107
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: NP_958915.1
• Gene: mapk3 / 399480
• ZFINID: ZDB-GENE-040121-1
• Length: 392
• Species: Danio rerio
• Alignment Length: 312
• Identity: 111/312 - (35%)
• Similarity: 166/312 - (53%)
• Gaps: 43/312 - (13%)

  Fly    14 IGEGTYGIVYKARSNSTGQDVALKKIR-LEGETEGVPSTAIREISLLKNLKHPNVVQLFDVVISG 77
            ||||.||:|..|..|.....||:|||. .|.:|  .....:|||.:|....|.|::.:.|::.:.
Zfish    62 IGEGAYGMVCSAFDNVNKIRVAIKKISPFEHQT--YCQRTLREIKILLRFHHENIIGINDILRAR 124

  Fly    78 N-----NLYMIFEYLNMDLKKLMDKKKDVFTPQL----IKSYMHQILDAVGFCHTNRILHRDLKP 133
            :     ::|::.:.:..||.||:.      |.||    |..:::|||..:.:.|:..:|||||||
Zfish   125 HIDYMRDVYIVQDLMETDLYKLLK------TQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKP 183

  Fly   134 QNLLVDTAGKIKLADFGLARAFNVPMRAY----THEVVTLWYRAPEILLGTKFYSTGVDIWSLGC 194
            .|||::|...:|:.||||||..: |...:    |..|.|.|||||||:|.:|.|:..:||||:||
Zfish   184 SNLLINTTCDLKICDFGLARIAD-PEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGC 247

  Fly   195 IFSEMIMRRSLFPGDSEIDQLYRIFRTLSTPDE-----------TNWPGVTQLPDFKTKFPRWEG 248
            |.:||:..|.:|||...:|||..|...|.:|.:           .|:  :..||. |.|.| |
Zfish   248 ILAEMLSNRPIFPGKHYLDQLNHILGVLGSPSQDDLNCIINMKARNY--LQSLPQ-KPKIP-W-- 306

  Fly   249 TNMPQPITEHEAHELIMSMLCYDPNLRISAKDALQHAYFRNVQHVDHVALPV 300
             |...|..:::|.:|:..||.::|..||:.:.||.|.|..  |:.|....||
Zfish   307 -NKLFPKADNKALDLLDRMLTFNPLKRINVEQALAHPYLE--QYYDPSDEPV 355

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk2	NP_524420.1	STKc_CDK1_CdkB_like	8..287	CDD:270829	106/297 (36%)
mapk3	NP_958915.1	STKc_ERK1_2_like	50..384	CDD:270839	111/312 (36%)