DRSC/TRiP Functional Genomics Resources

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Protein Alignment Cdk2 and Cdk8

DIOPT Version :9

Sequence 1:NP_001163666.1 Gene:Cdk2 / 42453 FlyBaseID:FBgn0004107 Length:314 Species:Drosophila melanogaster
Sequence 2:NP_536735.2 Gene:Cdk8 / 39157 FlyBaseID:FBgn0015618 Length:454 Species:Drosophila melanogaster


Alignment Length:315 Identity:114/315 - (36%)
Similarity:180/315 - (57%) Gaps:43/315 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly    13 KIGEGTYGIVYKA--RSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNLKHPNVVQLFDVVI 75
            |:|.||||.||||  :..|.|::.|||:|    :..|:..:|.|||:||:.|||.||:.|..|.:
  Fly    26 KVGRGTYGHVYKAKWKETSDGKEYALKQI----DGTGLSMSACREIALLRELKHQNVITLIRVFL 86

  Fly    76 SGNN--LYMIFEYLNMDLKKLMD-------KKKDVFTPQ-LIKSYMHQILDAVGFCHTNRILHRD 130
            |.|:  ::::.:|...||..::.       .||.|..|: ::||.::||||.:.:.|:|.:||||
  Fly    87 SHNDRKVFLLIDYAEHDLWHIIKFHRAAKATKKQVVVPRGMVKSLLYQILDGIHYLHSNWVLHRD 151

  Fly   131 LKPQNLLV----DTAGKIKLADFGLARAFNVPMRAYTH---EVVTLWYRAPEILLGTKFYSTGVD 188
            |||.|:||    :..|::|:||.|.||.||.|::....   .|||.||||||:|||.:.|:..:|
  Fly   152 LKPANILVMGDGNERGRVKIADMGFARLFNAPLKPLADLDPVVVTFWYRAPELLLGARHYTKAID 216

  Fly   189 IWSLGCIFSEMIMRRSLFPGDSE---------IDQLYRIFRTLSTPDETNWPGVTQLPDFKT--- 241
            ||::||||:|::....:|....|         .|||.|||..:..|.:.:|..:.::|:..|   
  Fly   217 IWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQDKDWEDIKKMPEHHTLTK 281

  Fly   242 --KFPRWEGTNMPQPITEH------EAHELIMSMLCYDPNLRISAKDALQHAYFR 288
              |...:...::.:.:..|      :|..|:..:|..|||.||:::.|:|..||:
  Fly   282 DFKRSTYSTCSLAKYMERHKIKPDSKAFHLLQKLLLMDPNKRITSEQAMQDQYFQ 336

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Cdk2NP_001163666.1 PLN00009 5..293 CDD:177649 114/315 (36%)
STKc_CDK1_CdkB_like 8..287 CDD:270829 112/312 (36%)
Cdk8NP_536735.2 STKc_CDK8_like 19..335 CDD:270834 112/312 (36%)
S_TKc 22..335 CDD:214567 112/312 (36%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45442412
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR24056
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
32.940

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