Protein Alignment Cdk2 and Cdk8

DIOPT Version :10

• Sequence 1: NP_524420.1
• Gene: Cdk2 / 42453
• FlyBaseID: FBgn0004107
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: NP_536735.2
• Gene: Cdk8 / 39157
• FlyBaseID: FBgn0015618
• Length: 454
• Species: Drosophila melanogaster
• Alignment Length: 315
• Identity: 114/315 - (36%)
• Similarity: 180/315 - (57%)
• Gaps: 43/315 - (13%)

  Fly    13 KIGEGTYGIVYKA--RSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNLKHPNVVQLFDVVI 75
            |:|.||||.||||  :..|.|::.|||:|    :..|:..:|.|||:||:.|||.||:.|..|.:
  Fly    26 KVGRGTYGHVYKAKWKETSDGKEYALKQI----DGTGLSMSACREIALLRELKHQNVITLIRVFL 86

  Fly    76 SGNN--LYMIFEYLNMDLKKLMD-------KKKDVFTPQ-LIKSYMHQILDAVGFCHTNRILHRD 130
            |.|:  ::::.:|...||..::.       .||.|..|: ::||.::||||.:.:.|:|.:||||
  Fly    87 SHNDRKVFLLIDYAEHDLWHIIKFHRAAKATKKQVVVPRGMVKSLLYQILDGIHYLHSNWVLHRD 151

  Fly   131 LKPQNLLV----DTAGKIKLADFGLARAFNVPMRAYTH---EVVTLWYRAPEILLGTKFYSTGVD 188
            |||.|:||    :..|::|:||.|.||.||.|::....   .|||.||||||:|||.:.|:..:|
  Fly   152 LKPANILVMGDGNERGRVKIADMGFARLFNAPLKPLADLDPVVVTFWYRAPELLLGARHYTKAID 216

  Fly   189 IWSLGCIFSEMIMRRSLFPGDSE---------IDQLYRIFRTLSTPDETNWPGVTQLPDFKT--- 241
            ||::||||:|::....:|....|         .|||.|||..:..|.:.:|..:.::|:..|
  Fly   217 IWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQDKDWEDIKKMPEHHTLTK 281

  Fly   242 --KFPRWEGTNMPQPITEH------EAHELIMSMLCYDPNLRISAKDALQHAYFR 288
              |...:...::.:.:..|      :|..|:..:|..|||.||:::.|:|..||:
  Fly   282 DFKRSTYSTCSLAKYMERHKIKPDSKAFHLLQKLLLMDPNKRITSEQAMQDQYFQ 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk2	NP_524420.1	STKc_CDK1_CdkB_like	8..287	CDD:270829	112/312 (36%)
Cdk8	NP_536735.2	STKc_CDK8_like	19..335	CDD:270834	112/312 (36%)