Protein Alignment Cdk2 and Cdk14

DIOPT Version :10

• Sequence 1: NP_524420.1
• Gene: Cdk2 / 42453
• FlyBaseID: FBgn0004107
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: NP_001382511.1
• Gene: Cdk14 / 362316
• RGDID: 1305544
• Length: 469
• Species: Rattus norvegicus
• Alignment Length: 323
• Identity: 146/323 - (45%)
• Similarity: 199/323 - (61%)
• Gaps: 22/323 - (6%)

  Fly     6 DNFQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNLKHPNVVQL 70
            |::::.||:|||:|..|||.:|...|:.||||.|||: |.||.|.|||||.||||.|||.|:|.|
  Rat   133 DSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQ-EEEGTPFTAIREASLLKGLKHANIVLL 196

  Fly    71 FDVVISGNNLYMIFEYLNMDLKKLMDKKKDVFTPQLIKSYMHQILDAVGFCHTNRILHRDLKPQN 135
            .|::.:...|.::|||::.||.:.|||......|..:|.::.|:|..:.:.|...||||||||||
  Rat   197 HDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQRYILHRDLKPQN 261

  Fly   136 LLVDTAGKIKLADFGLARAFNVPMRAYTHEVVTLWYRAPEILLGTKFYSTGVDIWSLGCIFSEMI 200
            ||:...|::||||||||||.:||...|::||||||||.|::|||:..|||.:|:|.:||||.|||
  Rat   262 LLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGVGCIFVEMI 326

  Fly   201 MRRSLFPGDSEI-DQLYRIFRTLSTPDETNWPGVTQLPDFK-TKFPRWEGTNMPQPITE----HE 259
            ...:.|||..:| |||.|||..|.||:|..||||..||.|| .:|..:...::.|...:    :.
  Rat   327 QGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPERFTVYSSKSLRQAWNKLSYVNH 391

  Fly   260 AHELIMSMLCYDPNLRISAKDALQHAYF-------------RNVQHVDHVALPVDPNAGSASR 309
            |.:|...:|...|..|:||:.||.|.||             .::..|.:|.|  .|.||.:.|
  Rat   392 AEDLASKLLQCSPKNRLSAQAALSHEYFSDLPPRLWELTDMSSIFTVPNVRL--QPEAGESMR 452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk2	NP_524420.1	STKc_CDK1_CdkB_like	8..287	CDD:270829	136/284 (48%)
Cdk14	NP_001382511.1	STKc_PFTAIRE1	129..431	CDD:143374	139/298 (47%)