DRSC/TRiP Functional Genomics Resources

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Protein Alignment Cdk2 and CG7236

DIOPT Version :9

Sequence 1:NP_001163666.1 Gene:Cdk2 / 42453 FlyBaseID:FBgn0004107 Length:314 Species:Drosophila melanogaster
Sequence 2:NP_608950.3 Gene:CG7236 / 33798 FlyBaseID:FBgn0031730 Length:438 Species:Drosophila melanogaster


Alignment Length:311 Identity:108/311 - (34%)
Similarity:168/311 - (54%) Gaps:29/311 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 LDNFQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNLKHPNVVQ 69
            :|.:::..::|||:||:|||.|...||..||:|:.....:...:...|:|||.|||||||||:|.
  Fly    47 MDRYEKLSRLGEGSYGVVYKCRDRETGALVAVKRFVESEDDPAIRKIALREIRLLKNLKHPNLVS 111

  Fly    70 LFDVVISGNNLYMIFEYLNMDLKKLMDKKKDVFTPQLIKSYMHQILDAVGFCHTNRILHRDLKPQ 134
            |.:|......|:::||:..:.:...:::........|.|...:|.|..|.:||....||||:||:
  Fly   112 LLEVFRRKRRLHLVFEFCELTVLHELERHPQGCPEHLTKQICYQTLLGVAYCHKQGCLHRDIKPE 176

  Fly   135 NLLVDTAGKIKLADFGLARAFNVPMRAYTHEVVTLWYRAPEILLGTKFYSTGVDIWSLGCIFSEM 199
            |:|:...|::||.|||.||..: |...||..|.|.||||||:|:|...|.|.||:|::||:|:|:
  Fly   177 NILLTAQGQVKLCDFGFARMLS-PGENYTDYVATRWYRAPELLVGDTQYGTPVDVWAIGCLFAEL 240

  Fly   200 IMRRSLFPGDSEIDQLYRIFRTLST---------PDETNWPGVT-----QLPDFKTKFPRWEGTN 250
            :...:|:||.|::||||.|.:||..         .....:.|:|     .|...:.|.|   ..:
  Fly   241 VRGEALWPGRSDVDQLYLIRKTLGDLLPRHIQIFGQNEYFKGITLPVPPTLEPLEDKMP---AKS 302

  Fly   251 MPQPITEHEAHELIMSMLCYDPNLRISAKDALQHAYF-------RNVQHVD 294
            ...|:|    .:.:...|..||..|.|.:...:|:||       |.::||:
  Fly   303 QQNPLT----IDFLKKCLDKDPTKRWSCEKLTKHSYFDDYIAKQRELEHVN 349

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Cdk2NP_001163666.1 PLN00009 5..293 CDD:177649 106/308 (34%)
STKc_CDK1_CdkB_like 8..287 CDD:270829 102/292 (35%)
CG7236NP_608950.3 STKc_CDKL1_4 48..335 CDD:270837 103/294 (35%)
Pkinase 50..335 CDD:278497 102/292 (35%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45442464
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR24056
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
32.940

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