Protein Alignment Cdk2 and Cdkl1

DIOPT Version :10

• Sequence 1: NP_524420.1
• Gene: Cdk2 / 42453
• FlyBaseID: FBgn0004107
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: NP_001020292.1
• Gene: Cdkl1 / 314198
• RGDID: 1305080
• Length: 352
• Species: Rattus norvegicus
• Alignment Length: 324
• Identity: 117/324 - (36%)
• Similarity: 177/324 - (54%)
• Gaps: 28/324 - (8%)

  Fly     5 LDNFQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGV-PSTAIREISLLKNLKHPNVV 68
            ::.:::..|||||:||:|:|.|:..|||.||:|:. ||.|.:.| ...|:|||.:||.|||||:|
  Rat     1 MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKRF-LETEDDPVIKKIALREIRMLKQLKHPNLV 64

  Fly    69 QLFDVVISGNNLYMIFEYLNMDLKKLMDKKKDVFTPQLIKSYMHQILDAVGFCHTNRILHRDLKP 133
            .|.:|......|:::|||.:..:...:|:.:......|:|:...|.|.||.|||.:..:|||:||
  Rat    65 SLLEVFRRKRRLHLVFEYCHHTVLHELDRYQRGVPEPLVKNITWQTLQAVNFCHKHNCIHRDVKP 129

  Fly   134 QNLLVDTAGKIKLADFGLARAFNVPMRAYTHEVVTLWYRAPEILLGTKFYSTGVDIWSLGCIFSE 198
            :|:|:.....|||.|||.||....|...||..|.|.|||:||:|:|...|...||:|::||:|:|
  Rat   130 ENILITKHSVIKLCDFGFARLLTGPGDYYTDYVATRWYRSPELLVGDTQYGPPVDVWAIGCVFAE 194

  Fly   199 MIMRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPDFKTKFPR---WEGTNMPQPITEHEA 260
            ::....|:||.|::||||.|.:||.          ..:|..:..|..   :.|..:|.| .:.|.
  Rat   195 LLSGVPLWPGKSDVDQLYLIRKTLG----------DLIPRHQQVFSMNQYFSGVKIPDP-EDMET 248

  Fly   261 HELIMSMLCY------------DPNLRISAKDALQHAYFRNVQHVDHVALPVDPNAGSASRLTR 312
            .||....:.|            ||..|::.:..|||.||.:::.|..:|.|.|.......|.:|
  Rat   249 LELKFPNISYSALGFLKGCLHMDPAERLTCEQLLQHPYFDSIRDVGELARPHDKPTRKTLRQSR 312

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk2	NP_524420.1	STKc_CDK1_CdkB_like	8..287	CDD:270829	109/294 (37%)
Cdkl1	NP_001020292.1	STKc_CDKL1_4	2..287	CDD:270837	109/296 (37%)
		[NKR]KIAxRE	45..51		1/5 (20%)