Protein Alignment Cdk2 and Cdk15

DIOPT Version :10

• Sequence 1: NP_524420.1
• Gene: Cdk2 / 42453
• FlyBaseID: FBgn0004107
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: NP_001418168.1
• Gene: Cdk15 / 301440
• RGDID: 1306205
• Length: 437
• Species: Rattus norvegicus
• Alignment Length: 290
• Identity: 135/290 - (46%)
• Similarity: 178/290 - (61%)
• Gaps: 13/290 - (4%)

  Fly     7 NFQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNLKHPNVVQLF 71
            ::...||:|||:|..|||..|...||.||||.|.:..| ||||.|||||.||||.|||.|:|.|.
  Rat   104 SYLNLEKLGEGSYATVYKGISRINGQLVALKVISMNAE-EGVPFTAIREASLLKGLKHANIVLLH 167

  Fly    72 DVVISGNNLYMIFEYLNMDLKKLMDKKKDVFTPQLIKSYMHQILDAVGFCHTNRILHRDLKPQNL 136
            |:|.:...|..:|||::.||.:.|.:......|..::.:|.|:|..:.:.|..|:||||||||||
  Rat   168 DIVHTKETLTFVFEYMHTDLAQYMSQHPGGLHPHNVRLFMFQLLRGLAYIHHQRVLHRDLKPQNL 232

  Fly   137 LVDTAGKIKLADFGLARAFNVPMRAYTHEVVTLWYRAPEILLGTKFYSTGVDIWSLGCIFSEMIM 201
            |:...|::||||||||||.::|.:.|:.||||||||.|:.|||...||:.:|||..||||.||..
  Rat   233 LLSHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQ 297

  Fly   202 RRSLFPGDSEI-DQLYRIFRTLSTPDETNWPGVTQLPDFKTKFPRWEGTNMPQPITE-------- 257
            .:.||||.|.| :||.:|:..|..|.|..||||::||::.   |.|.....||.:..
  Rat   298 GQPLFPGVSNILEQLEKIWEVLGVPTEDTWPGVSKLPNYN---PEWFPPPEPQSLQTVWNRLGGV 359

  Fly   258 HEAHELIMSMLCYDPNLRISAKDALQHAYF 287
            .||.:|...||...|..|:||::||.|.||
  Rat   360 PEAEDLASQMLKGFPRDRVSAQEALVHDYF 389

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk2	NP_524420.1	STKc_CDK1_CdkB_like	8..287	CDD:270829	133/287 (46%)
Cdk15	NP_001418168.1	STKc_PFTAIRE2	104..389	CDD:270852	133/288 (46%)