DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cdk2 and pef1

DIOPT Version :9

Sequence 1:	NP_001163666.1	Gene:	Cdk2 / 42453	FlyBaseID:	FBgn0004107	Length:	314	Species:	Drosophila melanogaster
Sequence 2:	NP_587921.1	Gene:	pef1 / 2539366	PomBaseID:	SPCC16C4.11	Length:	288	Species:	Schizosaccharomyces pombe

Alignment Length:	285	Identity:	144/285 - (50%)
Similarity:	203/285 - (71%)	Gaps:	5/285 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 NFQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNLKHPNVVQLF 71
            |:||.||:|||||..|||.::..||:.||||.||::.: ||.||||||||||:|.|:|||::.|.
pombe     2 NYQRLEKLGEGTYAHVYKGQNRVTGEIVALKVIRIDAD-EGTPSTAIREISLMKELRHPNIMSLS 65

  Fly    72 DVVISGNNLYMIFEYLNMDLKKLMDK--KKDVFTPQLIKSYMHQILDAVGFCHTNRILHRDLKPQ 134
            ||:.:.|.|.::|||:..||||.||.  .:....|..:|::..|:|..:.|||.||:||||||||
pombe    66 DVLQTENKLMLVFEYMEKDLKKYMDTYGNQGALPPSQVKNFTQQLLKGISFCHENRVLHRDLKPQ 130

  Fly   135 NLLVDTAGKIKLADFGLARAFNVPMRAYTHEVVTLWYRAPEILLGTKFYSTGVDIWSLGCIFSEM 199
            |||:::.|::|||||||||:..:|:..:::||||||||||::|||::.|||.:||||:|||.:||
pombe   131 NLLINSRGELKLADFGLARSIGIPVNTFSNEVVTLWYRAPDVLLGSRVYSTSIDIWSVGCIMAEM 195

  Fly   200 IMRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPDFKTKFPRWEGTNMPQ--PITEHEAHE 262
            ...|.||.|.:..|||.:|||.|.||.|.:|||::.||::|..||.::..::..  |..:....:
pombe   196 ATGRPLFAGSNNEDQLLKIFRLLGTPTEQSWPGISLLPEYKPTFPIYKAQDLAYLFPTFDPLGLD 260

  Fly   263 LIMSMLCYDPNLRISAKDALQHAYF 287
            |:..||...|.||.:.:||||||:|
pombe   261 LLRRMLRLQPELRTTGQDALQHAWF 285

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cdk2	NP_001163666.1	PLN00009	5..293	CDD:177649	144/285 (51%)
Cdk2	NP_001163666.1	STKc_CDK1_CdkB_like	8..287	CDD:270829	142/282 (50%)
pef1	NP_587921.1	PKc_like	2..285	CDD:304357	143/283 (51%)
pef1	NP_587921.1	PLN00009	3..285	CDD:177649	142/282 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0594
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000411
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100334
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R185
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.700