Protein Alignment Cdk2 and CDK20

DIOPT Version :10

• Sequence 1: NP_524420.1
• Gene: Cdk2 / 42453
• FlyBaseID: FBgn0004107
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: XP_047279074.1
• Gene: CDK20 / 23552
• HGNCID: 21420
• Length: 364
• Species: Homo sapiens
• Alignment Length: 329
• Identity: 127/329 - (38%)
• Similarity: 183/329 - (55%)
• Gaps: 32/329 - (9%)

  Fly     5 LDNFQRAEKIGEGTYGIVYKARS-------------NSTGQDVALKKIRLEGETEGVPSTAIREI 56
            :|.:....:||||.:|||:||:.             ..||:.|||||:.|....:|.|:.|:|||
Human     1 MDQYCILGRIGEGAHGIVFKAKHVEPRVGWQCLPSILQTGEIVALKKVALRRLEDGFPNQALREI 65

  Fly    57 SLLKNLK-HPNVVQLFDVVISGNNLYMIFEYLNMDLKKLMDKKKDVFTPQLIKSYMHQILDAVGF 120
            ..|:.:: :..||||..|...|....:.||::..||.:::...:.......:|||:..:|..|.|
Human    66 KALQEMEDNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAF 130

  Fly   121 CHTNRILHRDLKPQNLLVDTAGKIKLADFGLARAFNVP-MRAYTHEVVT-----LWYRAPEILLG 179
            ||.|.|:||||||.|||:..:|::|:|||||||.|:.. .|.|||:|.|     .||||||:|.|
Human   131 CHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATSPLPRRWYRAPELLYG 195

  Fly   180 TKFYSTGVDIWSLGCIFSEMIMRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPDF-KTKF 243
            .:.|..|||:||:|||..|::....||||.::|:||..:.|.|.||:...||.:|:|||: |..|
Human   196 ARQYDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNKISF 260

  Fly   244 PRWEGTNMPQPITE------HEAHELIMSMLCYDPNLRISAKDALQHAYFRNVQHVDHVA-LPVD 301
            ..    .:|.|:.|      .:|.:|:...|.|.|:.||:|..||.|.||.......|.: ||:.
Human   261 KE----QVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYFFTAPLPAHPSELPIP 321

  Fly   302 PNAG 305
            ...|
Human   322 QRLG 325

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk2	NP_524420.1	STKc_CDK1_CdkB_like	8..287	CDD:270829	120/305 (39%)
CDK20	XP_047279074.1	STKc_CCRK	3..307	CDD:270826	121/307 (39%)