Protein Alignment Cdk2 and CDK19

DIOPT Version :10

• Sequence 1: NP_524420.1
• Gene: Cdk2 / 42453
• FlyBaseID: FBgn0004107
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: NP_055891.1
• Gene: CDK19 / 23097
• HGNCID: 19338
• Length: 502
• Species: Homo sapiens
• Alignment Length: 316
• Identity: 116/316 - (36%)
• Similarity: 181/316 - (57%)
• Gaps: 45/316 - (14%)

  Fly    13 KIGEGTYGIVYKARSNSTGQD---VALKKIRLEGETEGVPSTAIREISLLKNLKHPNVVQLFDVV 74
            |:|.||||.||||| ...|:|   .|||:|    |..|:..:|.|||:||:.||||||:.|..|.
Human    26 KVGRGTYGHVYKAR-RKDGKDEKEYALKQI----EGTGISMSACREIALLRELKHPNVIALQKVF 85

  Fly    75 ISGNN--LYMIFEYLNMDLKKLMD-------KKKDVFTPQ-LIKSYMHQILDAVGFCHTNRILHR 129
            :|.::  ::::|:|...||..::.       .||.:..|: ::||.::||||.:.:.|.|.:|||
Human    86 LSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGIHYLHANWVLHR 150

  Fly   130 DLKPQNLLV----DTAGKIKLADFGLARAFNVPMRAYTH---EVVTLWYRAPEILLGTKFYSTGV 187
            ||||.|:||    ...|::|:||.|.||.||.|::....   .|||.||||||:|||.:.|:..:
Human   151 DLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAI 215

  Fly   188 DIWSLGCIFSEMIMRRSLFPGDSE---------IDQLYRIFRTLSTPDETNWPGVTQLPDFKT-- 241
            |||::||||:|::....:|....|         .|||.|||..:..|.:.:|..:.::|::.|
Human   216 DIWAIGCIFAELLTSEPIFHCRQEDIKTSNPFHHDQLDRIFSVMGFPADKDWEDIRKMPEYPTLQ 280

  Fly   242 -KFPR--WEGTNMPQPITEHEAHE------LIMSMLCYDPNLRISAKDALQHAYFR 288
             .|.|  :..:::.:.:.:|:...      |:..:|..||..||:::.|||..||:
Human   281 KDFRRTTYANSSLIKYMEKHKVKPDSKVFLLLQKLLTMDPTKRITSEQALQDPYFQ 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk2	NP_524420.1	STKc_CDK1_CdkB_like	8..287	CDD:270829	114/313 (36%)
CDK19	NP_055891.1	STKc_CDC2L6	18..335	CDD:270850	114/313 (36%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	359..502