Protein Alignment Cdk2 and dyf-18

DIOPT Version :10

• Sequence 1: NP_524420.1
• Gene: Cdk2 / 42453
• FlyBaseID: FBgn0004107
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: NP_502232.2
• Gene: dyf-18 / 186662
• WormBaseID: WBGene00010349
• Length: 323
• Species: Caenorhabditis elegans
• Alignment Length: 324
• Identity: 110/324 - (33%)
• Similarity: 167/324 - (51%)
• Gaps: 50/324 - (15%)

  Fly     1 MTTILDNFQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTA----IREISLLKN 61
            |.:.:..::..:..|.|.:|:|..||...|.:.||:|:|.       ||:.:    .||||.|:|
 Worm     1 MPSSIYRYETIQVAGRGAFGLVVIARDTLTSKRVAIKRIM-------VPNVSKVSLAREISCLRN 58

  Fly    62 LKHPNVVQLFDVVISGNNLYMIFEYLNMDLKKLMDKKKDVFTPQLIKSYMHQILDAVGFCHTNRI 126
            |.|.|:::|.|...|.:.:.::.|.:...|..::..|....|.|..:.|..|||..:.:.|:..|
 Worm    59 LHHRNILKLLDCFPSADLMSIVTEEVPYTLGDIIKDKTRPKTEQFNRWYYTQILSGIAYLHSKEI 123

  Fly   127 LHRDLKPQNLLVDTAGKIKLADFGLARAFNVPM---RAYTHEVVTLWYRAPEILLGTKFYSTGVD 188
            :|||:||:|:||.:...:|:||||.| .|.:|.   :.|...|.|.||||||:|.|:|.|...||
 Worm   124 MHRDIKPENILVTSRNVVKIADFGQA-CFYMPKDPNQEYDVNVATRWYRAPELLFGSKKYKPDVD 187

  Fly   189 IWSLGCIFSEMIMRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPD-----FKTKFPR--W 246
            ||::|||.:|::..:.:|||.||::|:..||..|.||:|.|||....:||     |:.|.||  |
 Worm   188 IWAIGCILAELVRGKPIFPGRSELEQISIIFGVLGTPNEDNWPNWRTMPDANKLLFEPKEPRNNW 252

  Fly   247 E--------GTNMPQPITEH-------EAHELI------MSMLCYDPNLRISAK-------DAL 282
            .        ..|..:.:..|       :|.||:      ..:...:||.|||.|       |||
 Worm   253 TEILLCKEISNNFTEFLGSHLQFFKRLKASELLKEPWIKQGLPLVEPNYRISKKSTRRNQRDAL 316

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk2	NP_524420.1	STKc_CDK1_CdkB_like	8..287	CDD:270829	109/317 (34%)
dyf-18	NP_502232.2	Protein Kinases, catalytic domain	7..289	CDD:473864	100/289 (35%)