Protein Alignment Cdk2 and cdk-4

DIOPT Version :9

• Sequence 1: NP_001163666.1
• Gene: Cdk2 / 42453
• FlyBaseID: FBgn0004107
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: NP_510256.1
• Gene: cdk-4 / 181472
• WormBaseID: WBGene00000406
• Length: 342
• Species: Caenorhabditis elegans
• Alignment Length: 321
• Identity: 115/321 - (35%)
• Similarity: 182/321 - (56%)
• Gaps: 28/321 - (8%)

  Fly     5 LDNFQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNL---KHPN 66
            :.:||..:.:|:|.||.||:.||...|:|.|||:|.:..:.||:|.:.:|||:::|:|   .|||
 Worm    35 MKDFQIHQALGKGAYGNVYRVRSLHDGKDYALKQIMISSKNEGIPQSVLREITVMKHLARKAHPN 99

  Fly    67 VVQL------FDVVISGNNLYMIFEYLNMDLKKLMDKKKDVFTPQLIKSYMHQILDAVGFCHTNR 125
            ::.|      .|.|.:...:.||.|..:.||...:.........|..|....||:.|:.|.||:.
 Worm   100 IISLKSVFHQLDPVRAILKINMIMERCDWDLHTFLRNIPRGVPEQQAKHVTAQIVRALDFLHTHS 164

  Fly   126 ILHRDLKPQNLLVDTAGKIKLADFGLARAFNVPMRAYTHEVVTLWYRAPEILLGTKFYSTGVDIW 190
            |:||||||||:|::....:|||||||::.:: ...|:|..|||||||:||:|| ..:|::.||:|
 Worm   165 IIHRDLKPQNILLNRDQTVKLADFGLSKEYS-NTTAFTTLVVTLWYRSPEVLL-QSYYNSTVDMW 227

  Fly   191 SLGCIFSEMIMRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPDFKTKFPRWEGTNMP--Q 253
            :||||.||:..|:.||.|.:|.:||..||:.:.||...:||..:.:.  :..||::..||:.  .
 Worm   228 ALGCIVSEIYCRQPLFVGQNEAEQLTDIFKKMGTPVGKDWPSESVIA--RDSFPQYRPTNLKDLS 290

  Fly   254 PITEHEAHELIMSMLCYDPNLRISAKDALQHAYFRNVQHVDHVALPVDPNAGSASRLTRLV 314
            |....:|.|.:...|.||.:.|:||:.||.|.:.:             |...:.||:.:.:
 Worm   291 PQMSKQAIEFVQQCLRYDHSKRLSARGALSHPFLK-------------PAVATKSRVLKQI 338

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk2	NP_001163666.1	PLN00009	5..293	CDD:177649	112/298 (38%)
		STKc_CDK1_CdkB_like	8..287	CDD:270829	112/289 (39%)
cdk-4	NP_510256.1	PKc_like	38..324	CDD:304357	112/289 (39%)
		S_TKc	38..324	CDD:214567	112/289 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24056
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010