Protein Alignment Cdk2 and cdk-11.2

DIOPT Version :10

• Sequence 1: NP_524420.1
• Gene: Cdk2 / 42453
• FlyBaseID: FBgn0004107
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: NP_509746.2
• Gene: cdk-11.2 / 181247
• WormBaseID: WBGene00013917
• Length: 668
• Species: Caenorhabditis elegans
• Alignment Length: 316
• Identity: 123/316 - (38%)
• Similarity: 179/316 - (56%)
• Gaps: 36/316 - (11%)

  Fly    14 IGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREIS-LLKNLKHPNVVQLFDVVISG 77
            |.|||||.|::.::..|.:.||||:.::|.|.||.|.||:|||: |||...|.|:|.:.::::..
 Worm   310 IAEGTYGEVFRGKNTRTDEVVALKRFKMEKEKEGFPITALREINMLLKAGAHENIVNVKEILVGS 374

  Fly    78 --NNLYMIFEYLNMDLKKLMDK---KKDVFTPQLIKSYMHQILDAVGFCHTNRILHRDLKPQNLL 137
              ..:||..||:..|:|.|:||   :...|.....|:.|.|:|..:...|...|||||||..|||
 Worm   375 TKTEVYMAMEYVEHDVKSLIDKMRSRNQRFKTGQQKTLMSQLLSGIEHMHKLWILHRDLKTSNLL 439

  Fly   138 VDTAGKIKLADFGLARAF----NVPMR-AYTHEVVTLWYRAPEILLGTKFYSTGVDIWSLGCIFS 197
            :..:|.:|:|||||||.:    ::..| ..|..|||||||:||:||..|.|||.||:||:|||.:
 Worm   440 ISHSGILKIADFGLAREYGEARDIEKRMKLTPIVVTLWYRSPELLLEPKTYSTPVDMWSIGCIMA 504

  Fly   198 EMIMRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPDFKTKFPRWEGTNMP---------- 252
            |.||.:.:|.||||.:|:::||:.:.||.|..||.:.:|       ..|.....|
 Worm   505 EFIMMKPMFQGDSEPNQVHQIFQMMGTPTEQIWPDIKEL-------KVWNMVEFPPVKPGQLRRI 562

  Fly   253 ---QPITEHEAHELIMSMLCYDPNLRISAKDALQHAYFRNVQHVDHVA---LPVDP 302
               :.:......:|:..|||.:|..|::|.:||||.:|.  :|...|.   |||.|
 Worm   563 FKGEKLVNETGFDLLNGMLCLNPANRLTASEALQHDWFS--EHPKAVPPEDLPVYP 616

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk2	NP_524420.1	STKc_CDK1_CdkB_like	8..287	CDD:270829	116/296 (39%)
cdk-11.2	NP_509746.2	Protein Kinases, catalytic domain	298..600	CDD:473864	116/296 (39%)