Protein Alignment Cdk2 and cdk-5

DIOPT Version :10

• Sequence 1: NP_524420.1
• Gene: Cdk2 / 42453
• FlyBaseID: FBgn0004107
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: NP_499783.1
• Gene: cdk-5 / 176774
• WormBaseID: WBGene00000407
• Length: 292
• Species: Caenorhabditis elegans
• Alignment Length: 291
• Identity: 148/291 - (50%)
• Similarity: 199/291 - (68%)
• Gaps: 5/291 - (1%)

  Fly     7 NFQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNLKHPNVVQLF 71
            |:.:.|||||||||.|:|||:.::|:.||||::||:.:.|||||:|:|||.:|:.|||.|||:|:
 Worm     3 NYDKMEKIGEGTYGTVFKARNKNSGEIVALKRVRLDDDDEGVPSSALREICILRELKHRNVVRLY 67

  Fly    72 DVVISGNNLYMIFEYLNMDLKKLMDKKKDVFTPQLIKSYMHQILDAVGFCHTNRILHRDLKPQNL 136
            |||.|.|.|.::|||.:.||||..|........|..:|.|.|:|..:.|||.:.:||||||||||
 Worm    68 DVVHSENKLTLVFEYCDQDLKKFFDSLNGYMDAQTARSLMLQLLRGLSFCHAHHVLHRDLKPQNL 132

  Fly   137 LVDTAGKIKLADFGLARAFNVPMRAYTHEVVTLWYRAPEILLGTKFYSTGVDIWSLGCIFSEMI- 200
            |::|.|.:|||||||||||.||:|.::.||||||||.|::|.|.|.|:|.:|:||.||||:|:.
 Worm   133 LINTNGTLKLADFGLARAFGVPVRCFSAEVVTLWYRPPDVLFGAKLYNTSIDMWSAGCIFAEISN 197

  Fly   201 MRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPDFKTKFPRWEGT---NMPQPITEHEAHE 262
            ..|.||||....|||.|||:.|.:|.|.|||.:|||||:| .:|.:..|   :...|.......:
 Worm   198 AGRPLFPGADVDDQLKRIFKQLGSPSEDNWPSITQLPDYK-PYPIYHPTLTWSQIVPNLNSRGRD 261

  Fly   263 LIMSMLCYDPNLRISAKDALQHAYFRNVQHV 293
            |:..:|..:|..||.|..||:||||.:...|
 Worm   262 LLQKLLVCNPAGRIDADAALRHAYFADTSDV 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk2	NP_524420.1	STKc_CDK1_CdkB_like	8..287	CDD:270829	144/282 (51%)
cdk-5	NP_499783.1	STKc_CDK5	3..286	CDD:143344	145/283 (51%)