Protein Alignment Cdk2 and mpk-1

DIOPT Version :10

• Sequence 1: NP_524420.1
• Gene: Cdk2 / 42453
• FlyBaseID: FBgn0004107
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: NP_001022584.1
• Gene: mpk-1 / 175545
• WormBaseID: WBGene00003401
• Length: 444
• Species: Caenorhabditis elegans
• Alignment Length: 306
• Identity: 106/306 - (34%)
• Similarity: 160/306 - (52%)
• Gaps: 31/306 - (10%)

  Fly    14 IGEGTYGIVYKARSNSTGQDVALKKIR-LEGETEGVPSTAIREISLLKNLKHPNVVQLFDVVISG 77
            ||||.||:|..|....|...||:|||. .|.:|  .....:|||.:|...||.|::.:.:::.|.
 Worm   102 IGEGAYGMVASALDTITRDRVAIKKISPFEHQT--FCQRTLREIKILNRFKHENIINIQEIIRSE 164

  Fly    78 -----NNLYMIFEYLNMDLKKLMDKKKDVFTPQLIKSYMHQILDAVGFCHTNRILHRDLKPQNLL 137
                 .::|::...:..||.||:..:|  .:...:..:::|||..:.:.|:..:|||||||.|||
 Worm   165 TVDSLKDIYIVQCLMETDLYKLLKTQK--LSNDHVCYFLYQILRGLKYIHSANVLHRDLKPSNLL 227

  Fly   138 VDTAGKIKLADFGLARAFNVPMRAY----THEVVTLWYRAPEILLGTKFYSTGVDIWSLGCIFSE 198
            ::|...:|:.||||||..: |...:    |..|.|.|||||||:|.:|.|:..:|:||:|||.:|
 Worm   228 LNTTCDLKICDFGLARVTD-PQTDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDVWSVGCILAE 291

  Fly   199 MIMRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGV---------TQLPDFKTKFPRWEGTNMPQP 254
            |:..|.||||...:|||..|...:.:|...:...:         ..|| .|.|.| |...   .|
 Worm   292 MLSNRPLFPGKHYLDQLNLILAVVGSPSNADLQCIINDKARSYLISLP-HKPKQP-WARL---YP 351

  Fly   255 ITEHEAHELIMSMLCYDPNLRISAKDALQHAYFRNVQHVDHVALPV 300
            ..:..|.:|:..||.::|:.||..:.||.|.|..  |:.|....||
 Worm   352 GADPRALDLLDKMLTFNPHNRIDIEQALAHPYLE--QYYDPGDEPV 395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk2	NP_524420.1	STKc_CDK1_CdkB_like	8..287	CDD:270829	101/291 (35%)
mpk-1	NP_001022584.1	STKc_ERK1_2_like	90..422	CDD:270839	106/306 (35%)