Protein Alignment Cdk2 and Cdk7

DIOPT Version :10

• Sequence 1: NP_524420.1
• Gene: Cdk2 / 42453
• FlyBaseID: FBgn0004107
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: NP_001385585.1
• Gene: Cdk7 / 171150
• RGDID: 621124
• Length: 346
• Species: Rattus norvegicus
• Alignment Length: 292
• Identity: 129/292 - (44%)
• Similarity: 185/292 - (63%)
• Gaps: 16/292 - (5%)

  Fly     8 FQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETE---GVPSTAIREISLLKNLKHPNVVQ 69
            :::.:.:|||.:..|||||..:|.|.||:|||:|...:|   |:..||:|||.||:.|.|||::.
  Rat    12 YEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIG 76

  Fly    70 LFDVVISGNNLYMIFEYLNMDLKKLMDKKKDVFTPQLIKSYMHQILDAVGFCHTNRILHRDLKPQ 134
            |.|.....:|:.::|:::..||:.::.....|.||..||:||...|..:.:.|.:.||||||||.
  Rat    77 LLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPN 141

  Fly   135 NLLVDTAGKIKLADFGLARAFNVPMRAYTHEVVTLWYRAPEILLGTKFYSTGVDIWSLGCIFSEM 199
            |||:|..|.:||||||||::|..|.|||||:|||.||||||:|.|.:.|..|||:|::|||.:|:
  Rat   142 NLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAEL 206

  Fly   200 IMRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPDFKTKFPRWEGTNMPQPITEH------ 258
            ::|....||||::|||.|||.||.||.|..||.:..|||:.| |..:.|..:     :|
  Rat   207 LLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVT-FKSFPGIPL-----QHIFIAAG 265

  Fly   259 -EAHELIMSMLCYDPNLRISAKDALQHAYFRN 289
             :..|||..:..::|..||:|..||:..||.|
  Rat   266 DDLLELIQGLFLFNPCTRITASQALRTKYFSN 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk2	NP_524420.1	STKc_CDK1_CdkB_like	8..287	CDD:270829	126/288 (44%)
Cdk7	NP_001385585.1	STKc_CDK7	11..308	CDD:270833	129/292 (44%)