Protein Alignment Cdk2 and CSNK2A1

DIOPT Version :10

• Sequence 1: NP_524420.1
• Gene: Cdk2 / 42453
• FlyBaseID: FBgn0004107
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: NP_001886.1
• Gene: CSNK2A1 / 1457
• HGNCID: 2457
• Length: 391
• Species: Homo sapiens
• Alignment Length: 313
• Identity: 98/313 - (31%)
• Similarity: 162/313 - (51%)
• Gaps: 50/313 - (15%)

  Fly     6 DNFQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAI-REISLLKNLK-HPNVV 68
            |::|...|:|.|.|..|::|.:.:..:.|.:|.::      .|....| |||.:|:||: .||::
Human    37 DDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILK------PVKKKKIKREIKILENLRGGPNII 95

  Fly    69 QLFDVVIS--GNNLYMIFEYL-NMDLKKLMDKKKDVFTPQLIKSYMHQILDAVGFCHTNRILHRD 130
            .|.|:|..  .....::||:: |.|.|:|.    ...|...|:.||::||.|:.:||:..|:|||
Human    96 TLADIVKDPVSRTPALVFEHVNNTDFKQLY----QTLTDYDIRFYMYEILKALDYCHSMGIMHRD 156

  Fly   131 LKPQNLLVD-TAGKIKLADFGLARAFNVPMRAYTHEVVTLWYRAPEILLGTKFYSTGVDIWSLGC 194
            :||.|:::| ...|::|.|:|||..:: |.:.|...|.:.:::.||:|:..:.|...:|:|||||
Human   157 VKPHNVMIDHEHRKLRLIDWGLAEFYH-PGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGC 220

  Fly   195 IFSEMIMRRS-LFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPDFKTKF--------------- 243
            :.:.||.|:. .|.|....|||.||.:.|.|.|         |.|:..|:
Human   221 MLASMIFRKEPFFHGHDNYDQLVRIAKVLGTED---------LYDYIDKYNIELDPRFNDILGRH 276

  Fly   244 --PRWE----GTNMPQPITEHEAHELIMSMLCYDPNLRISAKDALQHAYFRNV 290
              .|||    ..|  |.:...||.:.:..:|.||...|::|::|::|.||..|
Human   277 SRKRWERFVHSEN--QHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTV 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk2	NP_524420.1	STKc_CDK1_CdkB_like	8..287	CDD:270829	94/306 (31%)
CSNK2A1	NP_001886.1	STKc_CK2_alpha	20..325	CDD:271034	96/309 (31%)
		Interaction with beta subunit. /evidence=ECO:0000250	36..41		1/3 (33%)