Protein Alignment Cdk2 and Cdk8

DIOPT Version :10

• Sequence 1: NP_524420.1
• Gene: Cdk2 / 42453
• FlyBaseID: FBgn0004107
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: XP_319061.4
• Gene: Cdk8 / 1279351
• VectorBaseID: AGAMI1_000562
• Length: 515
• Species: Anopheles gambiae
• Alignment Length: 314
• Identity: 116/314 - (36%)
• Similarity: 178/314 - (56%)
• Gaps: 43/314 - (13%)

  Fly    13 KIGEGTYGIVYKAR--SNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNLKHPNVVQLFDVVI 75
            |:|.||||.|||||  ..:..:|.|||:|    |..|:..:|.|||:||:.||||||:.|..|.:
Mosquito    32 KVGRGTYGHVYKARRKEGNDAKDYALKQI----EGTGLSMSACREIALLRELKHPNVINLIRVFL 92

  Fly    76 S--GNNLYMIFEYLNMDLKKLMD-------KKKDVFTPQ-LIKSYMHQILDAVGFCHTNRILHRD 130
            |  ...::::|:|...||..::.       .||.|..|: ::||.::||||.:.:.|:|.:||||
Mosquito    93 SHTDRKVWLLFDYAEHDLWHIIKFHRAAKATKKPVMVPKGMVKSLLYQILDGIHYLHSNWVLHRD 157

  Fly   131 LKPQNLLV----DTAGKIKLADFGLARAFNVPMRAYTH---EVVTLWYRAPEILLGTKFYSTGVD 188
            |||.|:||    :..|::|:||.|.||.||.|::....   .|||.||||||:|||.:.|:..:|
Mosquito   158 LKPANILVMGEGNERGRVKIADMGFARLFNAPLKPLADLDPVVVTFWYRAPELLLGARHYTKAID 222

  Fly   189 IWSLGCIFSEMIMRRSLFPGDSE---------IDQLYRIFRTLSTPDETNWPGVTQLPDFKT--- 241
            ||::||||:|::....:|....|         .|||.|||..:..|.:.:|..:.::|:..|
Mosquito   223 IWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQDKDWEDIRKMPEHHTLTK 287

  Fly   242 --KFPRWEGTNMPQPITEH------EAHELIMSMLCYDPNLRISAKDALQHAYF 287
              |...:...::.:.:..|      :|..|:..:|..|||.||:::.|:|..||
Mosquito   288 DFKRSNYASCSLVKYMERHKIKPDSKAFHLLQKLLLMDPNKRITSEQAMQDPYF 341

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk2	NP_524420.1	STKc_CDK1_CdkB_like	8..287	CDD:270829	114/312 (37%)
Cdk8	XP_319061.4	None