Protein Alignment Cdk2 and Cdk12

DIOPT Version :10

• Sequence 1: NP_524420.1
• Gene: Cdk2 / 42453
• FlyBaseID: FBgn0004107
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: XP_061498912.1
• Gene: Cdk12 / 1278447
• VectorBaseID: AGAMI1_003914
• Length: 1490
• Species: Anopheles gambiae
• Alignment Length: 303
• Identity: 128/303 - (42%)
• Similarity: 179/303 - (59%)
• Gaps: 25/303 - (8%)

  Fly     8 FQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNLKHPNVVQLFD 72
            |...|:|||||||.||||:...|.:.|||||:|||.|.||.|.||:|||.:|:.|.|.|:|.|.:
Mosquito  1125 FDMLEQIGEGTYGQVYKAKDQQTNELVALKKVRLEHEKEGFPITAVREIKILRQLNHQNIVNLRE 1189

  Fly    73 VVI----------SGNNLYMIFEYLNMDLKKLMDKKKDVFTPQLIKSYMHQILDAVGFCHTNRIL 127
            :|.          ...:.|::|||::.||..|::.....|..|...|.|.|:||.:.:||....|
Mosquito  1190 IVTDKQDALEFRKDKGSFYLVFEYMDHDLMGLLESGMVDFNEQNNASIMRQLLDGLNYCHKKNFL 1254

  Fly   128 HRDLKPQNLLVDTAGKIKLADFGLARAFNVP--MRAYTHEVVTLWYRAPEILLGTKFYSTGVDIW 190
            |||:|..|:|::..|::|||||||||.:|..  .|.||::|:|||||.||:|||.:.|...:|:|
Mosquito  1255 HRDIKCSNILMNNRGEVKLADFGLARLYNADNRERPYTNKVITLWYRPPELLLGEERYGPAIDVW 1319

  Fly   191 SLGCIFSEMIMRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPDFKT--------KFPRWE 247
            |.|||..|:.:::.||..:.|..||..|.|...||....||.|.:||.|.|        :..|.:
Mosquito  1320 SCGCILGELFLKKPLFQANQEPAQLEMISRLCGTPTPAVWPNVIKLPLFHTLKSKKQYRRKLRED 1384

  Fly   248 GTNMPQPITEHEAHELIMSMLCYDPNLRISAKDALQHAYFRNV 290
            ...||.|     :.:|:.|||..||:.||:|:|||:..:.:||
Mosquito  1385 FVFMPMP-----SLDLLDSMLVLDPDRRITAEDALKSNWLKNV 1422

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk2	NP_524420.1	STKc_CDK1_CdkB_like	8..287	CDD:270829	126/298 (42%)
Cdk12	XP_061498912.1	None