Protein Alignment Cdk2 and Cdk5

DIOPT Version :10

• Sequence 1: NP_524420.1
• Gene: Cdk2 / 42453
• FlyBaseID: FBgn0004107
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: XP_315787.4
• Gene: Cdk5 / 1276441
• VectorBaseID: AGAMI1_003707
• Length: 289
• Species: Anopheles gambiae
• Alignment Length: 287
• Identity: 142/287 - (49%)
• Similarity: 201/287 - (70%)
• Gaps: 5/287 - (1%)

  Fly     5 LDNFQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNLKHPNVVQ 69
            :..:::.|||||||||.|:|.::..|.:.||||::||:.:.|||||:|:|||.|||.|||.|:|:
Mosquito     1 MQKYEKLEKIGEGTYGTVFKGKNRDTLEIVALKRVRLDEDDEGVPSSALREICLLKELKHKNIVR 65

  Fly    70 LFDVVISGNNLYMIFEYLNMDLKKLMDKKKDVFTPQLIKSYMHQILDAVGFCHTNRILHRDLKPQ 134
            |:||:.|...|.::||:.:.||||..|.......|.::||:|:|:|..:.|||::.:||||||||
Mosquito    66 LYDVLHSDKKLTLVFEHCDQDLKKYFDSLNGEIDPDVVKSFMYQLLRGLAFCHSHNVLHRDLKPQ 130

  Fly   135 NLLVDTAGKIKLADFGLARAFNVPMRAYTHEVVTLWYRAPEILLGTKFYSTGVDIWSLGCIFSEM 199
            |||::..|::|||||||||||.:|::.|:.||||||||.|::|.|.|.|:|.:|:||.||||:|:
Mosquito   131 NLLINKNGELKLADFGLARAFGIPVKCYSAEVVTLWYRPPDVLFGAKLYTTSIDMWSAGCIFAEL 195

  Fly   200 I-MRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPDFKTKFPRWEGT---NMPQPITEHEA 260
            . ..|.||||....|||.|||:.|.||:|.||||:|||.|:| .||.:..|   :...|....:.
Mosquito   196 ANAGRPLFPGSDVDDQLKRIFKLLGTPEEENWPGITQLSDYK-PFPLYPPTTSWSQVVPRLNSKG 259

  Fly   261 HELIMSMLCYDPNLRISAKDALQHAYF 287
            .:|:..:|...|.||:||:.|:.|.||
Mosquito   260 RDLLQKLLVCRPLLRLSAEQAMSHPYF 286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk2	NP_524420.1	STKc_CDK1_CdkB_like	8..287	CDD:270829	140/282 (50%)
Cdk5	XP_315787.4	STKc_CDK5	3..286	CDD:143344	140/283 (49%)