Protein Alignment Cdk2 and Cdk7

DIOPT Version :10

• Sequence 1: NP_524420.1
• Gene: Cdk2 / 42453
• FlyBaseID: FBgn0004107
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: NP_034004.2
• Gene: Cdk7 / 12572
• MGIID: 102956
• Length: 346
• Species: Mus musculus
• Alignment Length: 292
• Identity: 128/292 - (43%)
• Similarity: 184/292 - (63%)
• Gaps: 16/292 - (5%)

  Fly     8 FQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETE---GVPSTAIREISLLKNLKHPNVVQ 69
            :::.:.:|||.:..|||||..:|.|.||:|||:|...:|   |:..||:|||.||:.|.|||::.
Mouse    12 YEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIG 76

  Fly    70 LFDVVISGNNLYMIFEYLNMDLKKLMDKKKDVFTPQLIKSYMHQILDAVGFCHTNRILHRDLKPQ 134
            |.|.....:|:.::|:::..||:.::.....|.||..||:||...|..:.:.|.:.||||||||.
Mouse    77 LLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPN 141

  Fly   135 NLLVDTAGKIKLADFGLARAFNVPMRAYTHEVVTLWYRAPEILLGTKFYSTGVDIWSLGCIFSEM 199
            |||:|..|.:||||||||::|..|.|||||:|||.||||||:|.|.:.|..|||:|::|||.:|:
Mouse   142 NLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAEL 206

  Fly   200 IMRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPDFKTKFPRWEGTNMPQPITEH------ 258
            ::|....||||::|||.|||.||.||.|..||.:..|||:.| |..:.|..:     :|
Mouse   207 LLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVT-FKSFPGVPL-----QHIFIAAG 265

  Fly   259 -EAHELIMSMLCYDPNLRISAKDALQHAYFRN 289
             :..|||..:..::|..|.:|..||:..||.|
Mouse   266 DDLLELIQGLFLFNPCTRTTASQALKTKYFSN 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk2	NP_524420.1	STKc_CDK1_CdkB_like	8..287	CDD:270829	125/288 (43%)
Cdk7	NP_034004.2	STKc_CDK7	11..308	CDD:270833	128/292 (44%)