Protein Alignment Cdk2 and Cdk6

DIOPT Version :9

• Sequence 1: NP_001163666.1
• Gene: Cdk2 / 42453
• FlyBaseID: FBgn0004107
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: NP_034003.1
• Gene: Cdk6 / 12571
• MGIID: 1277162
• Length: 326
• Species: Mus musculus
• Alignment Length: 311
• Identity: 133/311 - (42%)
• Similarity: 197/311 - (63%)
• Gaps: 35/311 - (11%)

  Fly     6 DNFQRAE-------KIGEGTYGIVYKARS-NSTGQDVALKKIRLEGETEGVPSTAIREISLLKNL 62
            |:..||:       :||||.||.|:|||. .:.|:.||||::|::...||:|.:.|||:::|::|
Mouse     4 DSLSRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTSEEGMPLSTIREVAVLRHL 68

  Fly    63 ---KHPNVVQLFDV-VISGNN----LYMIFEYLNMDLKKLMDKKKDVFTP-QLIKSYMHQILDAV 118
               :|||||:|||| .:|..:    |.::||:::.||...:||..:...| :.||..|.|:|..:
Mouse    69 ETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLLRGL 133

  Fly   119 GFCHTNRILHRDLKPQNLLVDTAGKIKLADFGLARAFNVPMRAYTHEVVTLWYRAPEILLGTKFY 183
            .|.|::|::||||||||:||.::|:||||||||||.::..| |.|..||||||||||:||.:. |
Mouse   134 DFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQM-ALTSVVVTLWYRAPEVLLQSS-Y 196

  Fly   184 STGVDIWSLGCIFSEMIMRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLP--DFKTKFPRW 246
            :|.||:||:||||:||..|:.||.|.|::|||.:|...:..|.|.:||....||  .|.:|
Mouse   197 ATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDIIGLPGEEDWPRDVALPRQAFHSK---- 257

  Fly   247 EGTNMPQPI------TEHEAHELIMSMLCYDPNLRISAKDALQHAYFRNVQ 291
                ..|||      .:....:|::..|.::|..||||..||.|.||::::
Mouse   258 ----SAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYGALNHPYFQDLE 304

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk2	NP_001163666.1	PLN00009	5..293	CDD:177649	133/311 (43%)
		STKc_CDK1_CdkB_like	8..287	CDD:270829	130/303 (43%)
Cdk6	NP_034003.1	STKc_CDK6	11..300	CDD:270846	128/298 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0594
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810