Protein Alignment Cdk2 and Cdk11b

DIOPT Version :10

• Sequence 1: NP_524420.1
• Gene: Cdk2 / 42453
• FlyBaseID: FBgn0004107
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: NP_031687.2
• Gene: Cdk11b / 12537
• MGIID: 88353
• Length: 784
• Species: Mus musculus
• Alignment Length: 305
• Identity: 136/305 - (44%)
• Similarity: 194/305 - (63%)
• Gaps: 12/305 - (3%)

  Fly     5 LDNFQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNLKHPNVVQ 69
            ::.||...:|.|||||:||:|:...|.:.||||::::|.|.||.|.|::|||:.:...:|||:|.
Mouse   424 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVT 488

  Fly    70 LFDVVISGN--NLYMIFEYLNMDLKKLMDKKKDVFTPQLIKSYMHQILDAVGFCHTNRILHRDLK 132
            :.::|:..|  .:|::..|:..|||.||:..|..|.|..:|:.|.|:|..|...|.|.|||||||
Mouse   489 VREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLSGVKHLHDNWILHRDLK 553

  Fly   133 PQNLLVDTAGKIKLADFGLARAFNVPMRAYTHEVVTLWYRAPEILLGTKFYSTGVDIWSLGCIFS 197
            ..|||:..||.:|:.||||||.:..|::|||..||||||||||:|||.|.|||.||:||:||||.
Mouse   554 TSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFG 618

  Fly   198 EMIMRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPDF-KTKFPRWEGTNMPQ---PITEH 258
            |::.::.||||.|:|||:.:||:.|.||.|..|||...||.. |..|..:...|:.:   .:...
Mouse   619 ELLTQKPLFPGKSDIDQINKIFKDLGTPSEKIWPGYNDLPAVKKMTFSEYPYNNLRKRFGALLSD 683

  Fly   259 EAHELIMSMLCYDPNLRISAKDALQHAYFRNVQHVDHVALPVDPN 303
            :..:|:...|.|.|..||:|:|.|:|.|||      ...||:||:
Mouse   684 QGFDLMNKFLTYYPGRRINAEDGLKHEYFR------ETPLPIDPS 722

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk2	NP_524420.1	STKc_CDK1_CdkB_like	8..287	CDD:270829	129/284 (45%)
Cdk11b	NP_031687.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	18..401
		STKc_CDC2L1	421..712	CDD:173741	129/287 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	722..784		0/1 (0%)