Protein Alignment Cdk2 and Cdk1

DIOPT Version :10

• Sequence 1: NP_524420.1
• Gene: Cdk2 / 42453
• FlyBaseID: FBgn0004107
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: NP_031685.2
• Gene: Cdk1 / 12534
• MGIID: 88351
• Length: 297
• Species: Mus musculus
• Alignment Length: 296
• Identity: 170/296 - (57%)
• Similarity: 215/296 - (72%)
• Gaps: 12/296 - (4%)

  Fly     5 LDNFQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNLKHPNVVQ 69
            ::::.:.|||||||||:|||.|...|||.||:||||||.|.|||||||||||||||.|:|||:|.
Mouse     1 MEDYIKIEKIGEGTYGVVYKGRHRVTGQIVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVS 65

  Fly    70 LFDVVISGNNLYMIFEYLNMDLKKLMDK--KKDVFTPQLIKSYMHQILDAVGFCHTNRILHRDLK 132
            |.||::..:.||:|||:|:|||||.:|.  ........|:|||:||||..:.|||:.|:||||||
Mouse    66 LQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQFMDSSLVKSYLHQILQGIVFCHSRRVLHRDLK 130

  Fly   133 PQNLLVDTAGKIKLADFGLARAFNVPMRAYTHEVVTLWYRAPEILLGTKFYSTGVDIWSLGCIFS 197
            |||||:|..|.||||||||||||.:|:|.|||||||||||:||:|||:..|||.|||||:|.||:
Mouse   131 PQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFA 195

  Fly   198 EMIMRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPDFKTKFPRWEGTNMPQPITEHEAH- 261
            |:..::.||.||||||||:||||.|.||:...||.|..|.|:|..||:|:    |..:..|..:
Mouse   196 ELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWK----PGSLASHVKNL 256

  Fly   262 -----ELIMSMLCYDPNLRISAKDALQHAYFRNVQH 292
                 :|:..||.|||..|||.|.||:|.||.::.:
Mouse   257 DENGLDLLSKMLVYDPAKRISGKMALKHPYFDDLDN 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk2	NP_524420.1	STKc_CDK1_CdkB_like	8..287	CDD:270829	168/286 (59%)
Cdk1	NP_031685.2	STKc_CDK1_euk	3..287	CDD:270845	168/287 (59%)