Protein Alignment Cdk2 and Cdk20

DIOPT Version :10

• Sequence 1: NP_524420.1
• Gene: Cdk2 / 42453
• FlyBaseID: FBgn0004107
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: NP_444410.1
• Gene: Cdk20 / 105278
• MGIID: 2145349
• Length: 346
• Species: Mus musculus
• Alignment Length: 310
• Identity: 126/310 - (40%)
• Similarity: 181/310 - (58%)
• Gaps: 16/310 - (5%)

  Fly     5 LDNFQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNLKHPN-VV 68
            :|.:....:||||.:|||:||:...||:.|||||:.|....:|:|:.|:|||..|:.::... ||
Mouse     1 MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGIPNQALREIKALQEIEDSQYVV 65

  Fly    69 QLFDVVISGNNLYMIFEYLNMDLKKLMDKKKDVFTPQLIKSYMHQILDAVGFCHTNRILHRDLKP 133
            ||..|...|....:.||::..||.:::...:....|..:|||:..:|..|.|||.|.|:||||||
Mouse    66 QLKAVFPHGAGFVLAFEFMLSDLAEVVRHAQRPLAPAQVKSYLQMLLKGVAFCHANNIVHRDLKP 130

  Fly   134 QNLLVDTAGKIKLADFGLARAFNVP-MRAYTHEVVTLWYRAPEILLGTKFYSTGVDIWSLGCIFS 197
            .|||:..:|::|:|||||||.|:.. .|.|||:|.|.||||||:|.|.:.|..|||:|::|||..
Mouse   131 ANLLISASGQLKIADFGLARVFSPDGGRLYTHQVATRWYRAPELLYGARQYDQGVDLWAVGCIMG 195

  Fly   198 EMIMRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPDF-KTKFPRWEGTNMPQPITE---- 257
            |::....||||:::|:||..:.|.|.||....||.:|:|||: |..|..    ..|.|:.|
Mouse   196 ELLNGSPLFPGENDIEQLCCVLRILGTPSPRVWPEITELPDYNKISFKE----QAPVPLEEVLPD 256

  Fly   258 --HEAHELIMSMLCYDPNLRISAKDALQHAYFRNV---QHVDHVALPVDP 302
              .:|.:|:...|.|.|..||:|..||.|.||...   .|...:.:|..|
Mouse   257 ASPQALDLLGQFLLYPPRQRIAASQALLHQYFFTAPLPAHPSELPIPQRP 306

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk2	NP_524420.1	STKc_CDK1_CdkB_like	8..287	CDD:270829	120/287 (42%)
Cdk20	NP_444410.1	STKc_CCRK	3..289	CDD:270826	121/289 (42%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	298..324		2/9 (22%)