Protein Alignment Cdk2 and CDK6

DIOPT Version :9

• Sequence 1: NP_001163666.1
• Gene: Cdk2 / 42453
• FlyBaseID: FBgn0004107
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: NP_001138778.1
• Gene: CDK6 / 1021
• HGNCID: 1777
• Length: 326
• Species: Homo sapiens
• Alignment Length: 302
• Identity: 130/302 - (43%)
• Similarity: 194/302 - (64%)
• Gaps: 28/302 - (9%)

  Fly     8 FQRAEKIGEGTYGIVYKARS-NSTGQDVALKKIRLEGETEGVPSTAIREISLLKNL---KHPNVV 68
            ::...:||||.||.|:|||. .:.|:.||||::|::...||:|.:.|||:::|::|   :|||||
Human    13 YECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLETFEHPNVV 77

  Fly    69 QLFDV-VISGNN----LYMIFEYLNMDLKKLMDKKKDVFTP-QLIKSYMHQILDAVGFCHTNRIL 127
            :|||| .:|..:    |.::||:::.||...:||..:...| :.||..|.|:|..:.|.|::|::
Human    78 RLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLLRGLDFLHSHRVV 142

  Fly   128 HRDLKPQNLLVDTAGKIKLADFGLARAFNVPMRAYTHEVVTLWYRAPEILLGTKFYSTGVDIWSL 192
            ||||||||:||.::|:||||||||||.::..| |.|..||||||||||:||.:. |:|.||:||:
Human   143 HRDLKPQNILVTSSGQIKLADFGLARIYSFQM-ALTSVVVTLWYRAPEVLLQSS-YATPVDLWSV 205

  Fly   193 GCIFSEMIMRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLP--DFKTKFPRWEGTNMPQPI 255
            ||||:||..|:.||.|.|::|||.:|...:..|.|.:||....||  .|.:|        ..|||
Human   206 GCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWPRDVALPRQAFHSK--------SAQPI 262

  Fly   256 ------TEHEAHELIMSMLCYDPNLRISAKDALQHAYFRNVQ 291
                  .:....:|::..|.::|..||||..||.|.||::::
Human   263 EKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQDLE 304

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk2	NP_001163666.1	PLN00009	5..293	CDD:177649	130/302 (43%)
		STKc_CDK1_CdkB_like	8..287	CDD:270829	128/296 (43%)
CDK6	NP_001138778.1	STKc_CDK6	11..300	CDD:270846	128/296 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0594
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810