Protein Alignment Cdk2 and cdk6

DIOPT Version :10

• Sequence 1: NP_524420.1
• Gene: Cdk2 / 42453
• FlyBaseID: FBgn0004107
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: XP_002934637.2
• Gene: cdk6 / 100489734
• XenbaseID: XB-GENE-985427
• Length: 333
• Species: Xenopus tropicalis
• Alignment Length: 300
• Identity: 132/300 - (44%)
• Similarity: 194/300 - (64%)
• Gaps: 24/300 - (8%)

  Fly     8 FQRAEKIGEGTYGIVYKARS-NSTGQDVALKKIRLEGETEGVPSTAIREISLLKNL---KHPNVV 68
            ::...:||||.||.|:|||. .:.|:.||||::|::...||:|.:.|||:::|::|   :|||||
 Frog    15 YECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLETFEHPNVV 79

  Fly    69 QLFDV-VISGNN----LYMIFEYLNMDLKKLMDKKKDVFTP-QLIKSYMHQILDAVGFCHTNRIL 127
            :|||| .:|..:    |.::||:::.||...:||..|...| ::||..|.|:|..:.|.|::|::
 Frog    80 RLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPDPGVPSEIIKDMMLQLLRGLDFLHSHRVV 144

  Fly   128 HRDLKPQNLLVDTAGKIKLADFGLARAFNVPMRAYTHEVVTLWYRAPEILLGTKFYSTGVDIWSL 192
            ||||||||:||.:.|:||||||||||.::..| |.|..||||||||||:||.:. |:|.||:||:
 Frog   145 HRDLKPQNILVTSNGQIKLADFGLARIYSFQM-ALTSVVVTLWYRAPEVLLQSS-YATPVDLWSV 207

  Fly   193 GCIFSEMIMRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPDFKTKFPRWEGTNMPQPI-- 255
            ||||:||..|:.||.|:|::|||.:||..:..|:|..||....:|.....|      ..||||
 Frog   208 GCIFAEMFRRKPLFRGNSDVDQLGKIFDVIGLPEEEEWPHDVAVPRNAFHF------RQPQPIEN 266

  Fly   256 ----TEHEAHELIMSMLCYDPNLRISAKDALQHAYFRNVQ 291
                .:.:..:|::..|.:.|..||||..||.|.||.::|
 Frog   267 VVPGIDEQGKDLLIKCLTFSPANRISAYSALSHPYFHDLQ 306

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk2	NP_524420.1	STKc_CDK1_CdkB_like	8..287	CDD:270829	129/294 (44%)
cdk6	XP_002934637.2	STKc_CDK6	13..302	CDD:270846	129/294 (44%)