Protein Alignment Oct-TyrR and adrb1

DIOPT Version :10

• Sequence 1: NP_524419.2
• Gene: Oct-TyrR / 42452
• FlyBaseID: FBgn0004514
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: NP_001122161.1
• Gene: adrb1 / 557194
• ZFINID: ZDB-GENE-081022-145
• Length: 390
• Species: Danio rerio
• Alignment Length: 503
• Identity: 132/503 - (26%)
• Similarity: 197/503 - (39%)
• Gaps: 197/503 - (39%)

  Fly   100 LQLAVPEWEALLTALVLSVIIVLTIIGNILVILSVFTYKPLRIVQNFFIVSLAVADLTVALLVLP 164
            :.|.|.|...:...:::.:|:.:.::||||||:::...:.|:.:.|.||||||.|||.:.|||:|
Zfish    19 VDLNVSEQWLVGMGILMGLIVFVIVVGNILVIVAIARNQRLQTLTNVFIVSLACADLIMGLLVVP 83

  Fly   165 FNVAYSILGRWEFGIHLCKLWLTCDVLCCTSSILNLCAIALDRYWAITDPINYAQKRTVGRVLLL 229
            |..|..:.|.|.:|...|:.|::.||||.|:||..||.||:|||.||..|..|....|..|..::
Zfish    84 FGAALEVRGAWMYGSFFCEFWISLDVLCVTASIETLCVIAIDRYIAIISPFRYQSLLTKARAKVV 148

  Fly   230 ISGVWLLSLLISSPP-LIGWNDWPDE---FTSATPCELTSQRGYVIYSSLGSFFIPLAIMTIVYI 290
            :..||.:|.|:|.|| |:.|:...:|   :.:...|:..:.|.|.|.||:.||:|||.:|..||.
Zfish   149 VCAVWAISALVSFPPILMHWSQDSEETSCYENPECCDFVTNRAYAISSSIISFYIPLIVMIFVYA 213

  Fly   291 EIFVATRRRLRERARANKLNTIALKSTELEPMANSSPVAASNSGSKSRLLASWLCCGRDRAQFAT 355
            .::...:::|      ||:|.                                 |.||
Zfish   214 RVYREAKQQL------NKINK---------------------------------CEGR------- 232

  Fly   356 PMIQNDQESISSETHQPQDSSKAGPHGNSDPQQQHVVVLVKKSRRAKTKDSIKHGKTRGGRKSQS 420
              ..|:                   ||.
Zfish   233 --FYNN-------------------HGT------------------------------------- 239

  Fly   421 SSTCEPHGEQQLLPAGGDGGSCQPGGGHSGGGKSDAEISTESGSDPKGCIQVCVTQADEQTSLKL 485
                                :|:
Zfish   240 --------------------NCK------------------------------------------ 242

  Fly   486 TPPQSSTGVAAVSVTPLQKKTSGVNQFIEEKQKISLSKERRAARTLGIIMGVFVICWLPFFLMYV 550
                           |.:|:|:          ||...||::|.:|||||||.|.:||||||::.|
Zfish   243 ---------------PTRKRTT----------KILALKEQKALKTLGIIMGTFTLCWLPFFIVNV 282

  Fly   551 ILPFCQTCCPTNKFKNFITWLGYINSGLNPVIYTIFNLDYRRAFKRLL 598
            :..||........|. |:.||||:||..||:|| ..:.|:|:||||||
Zfish   283 VRVFCAQVVDKELFV-FLNWLGYVNSAFNPIIY-CRSPDFRKAFKRLL 328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oct-TyrR	NP_524419.2	7tmA_tyramine_octopamine_R-like	110..>294	CDD:320188	73/187 (39%)
		TM helix 1	111..137	CDD:320188	7/25 (28%)
		TM helix 2	144..170	CDD:320188	16/25 (64%)
		TM helix 3	182..212	CDD:320188	17/29 (59%)
		TM helix 4	224..247	CDD:320188	9/23 (39%)
		TM helix 5	266..294	CDD:320188	13/27 (48%)
		7tm_GPCRs	<519..594	CDD:475119	35/74 (47%)
		TM helix 6	528..550	CDD:410628	14/21 (67%)
		TM helix 7	562..587	CDD:410628	12/24 (50%)
adrb1	NP_001122161.1	7tm_GPCRs	30..324	CDD:475119	123/486 (25%)
		TM helix 1	31..55	CDD:320624	7/23 (30%)
		TM helix 2	64..86	CDD:320624	15/21 (71%)
		TM helix 3	102..124	CDD:320624	11/21 (52%)
		TM helix 4	147..163	CDD:320624	5/15 (33%)
		TM helix 5	190..213	CDD:320624	12/22 (55%)
		TM helix 6	260..282	CDD:320624	14/21 (67%)
		TM helix 7	293..318	CDD:320624	12/26 (46%)