| Sequence 1: | NP_001163494.1 | Gene: | Oct-TyrR / 42452 | FlyBaseID: | FBgn0004514 | Length: | 601 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_000855.1 | Gene: | HTR1D / 3352 | HGNCID: | 5289 | Length: | 377 | Species: | Homo sapiens |
| Alignment Length: | 522 | Identity: | 147/522 - (28%) |
|---|---|---|---|
| Similarity: | 224/522 - (42%) | Gaps: | 169/522 - (32%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 87 EGAVEELHASILGLQLAVPEWE-------ALLTALVLSVIIVLTIIGNILVILSVFTYKPLRIVQ 144
Fly 145 NFFIVSLAVADLTVALLVLPFNVAYSILGRWEFGIHLCKLWLTCDVLCCTSSILNLCAIALDRYW 209
Fly 210 AITDPINYAQKRTVGRVLLLISGVWLLSLLISSPPLIGWNDWPDEFTSATPCELTSQRGYVIYSS 274
Fly 275 LGSFFIPLAIMTIVYIEIFVATRRRLRERARANKLNTIALKSTELEPMANSSPVAASNSGSKSRL 339
Fly 340 LASWLCCGRDRAQFATPMIQNDQESISSETHQPQDSSKAGPHGNSDPQQQHVVVLVKKSRRAKTK 404
Fly 405 DSIKHGKTRGGRKSQSSSTCEPHGEQQLLPAGGDGGSCQPGGGHSGGGKSDAEISTESGSDPKGC 469
Fly 470 IQVCVTQADEQTSLKLTPPQSSTGVAAVSVTPLQKKTSGVNQFIEEKQKISLSKERRAARTLGII 534
Fly 535 MGVFVICWLPFFLMYVILPFCQTCC---PTNKFKNFITWLGYINSGLNPVIYTIFNLDYRRAFKR 596
Fly 597 LL 598 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Oct-TyrR | NP_001163494.1 | Zinc_peptidase_like | <113..244 | CDD:301362 | 61/130 (47%) |
| 7tm_1 | 126..>293 | CDD:278431 | 71/166 (43%) | ||
| HTR1D | NP_000855.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..23 | 4/13 (31%) | |
| 7tmA_5-HT1B_1D | 35..367 | CDD:320455 | 140/490 (29%) | ||
| TM helix 1 | 40..66 | CDD:320455 | 9/25 (36%) | ||
| TM helix 2 | 73..99 | CDD:320455 | 12/25 (48%) | ||
| TM helix 3 | 111..141 | CDD:320455 | 20/29 (69%) | ||
| Agonist binding. /evidence=ECO:0000250 | 114..123 | 4/8 (50%) | |||
| DRY motif, important for ligand-induced conformation changes. /evidence=ECO:0000250 | 135..137 | 1/1 (100%) | |||
| TM helix 4 | 153..176 | CDD:320455 | 10/23 (43%) | ||
| TM helix 5 | 194..223 | CDD:320455 | 12/28 (43%) | ||
| TM helix 6 | 294..324 | CDD:320455 | 16/29 (55%) | ||
| Agonist binding. /evidence=ECO:0000250 | 314..318 | 3/3 (100%) | |||
| TM helix 7 | 335..360 | CDD:320455 | 14/26 (54%) | ||
| NPxxY motif, important for ligand-induced conformation changes and signaling. /evidence=ECO:0000250 | 352..356 | 2/3 (67%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 1 | 1.000 | - | - | H20240 | |
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.910 | |||||