Protein Alignment Oct-TyrR and Taar7e

DIOPT Version :10

• Sequence 1: NP_524419.2
• Gene: Oct-TyrR / 42452
• FlyBaseID: FBgn0004514
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: NP_001010835.1
• Gene: Taar7e / 276742
• MGIID: 3527445
• Length: 358
• Species: Mus musculus
• Alignment Length: 528
• Identity: 118/528 - (22%)
• Similarity: 172/528 - (32%)
• Gaps: 209/528 - (39%)

  Fly    74 STAQADKDSAGECEGAVEELHASILGLQLAVPEWEALLTALVLSVIIVLTIIGNILVILSVFTYK 138
            |....|..||...|...|.|:.|.:....: |....:|.| |.....||.:.||:||:.|:..::
Mouse    14 SILSRDLFSATSAELCYENLNRSCVRSPYS-PGPRLILYA-VFGFGAVLAVCGNLLVMTSILHFR 76

  Fly   139 PLRIVQNFFIVSLAVADLTVALLVLPFNVAYSILGRWEFGIHLCKLWLTCDVLCCTSSILNLCAI 203
            .|....||.:.|||.||..|.|.|:||:...|:.|.|.||...|||....||..|:|||.:||.|
Mouse    77 QLHSPANFLVASLACADFLVGLTVMPFSTVRSVEGCWYFGEIYCKLHTCFDVSFCSSSIFHLCFI 141

  Fly   204 ALDRYWAITDPINYAQKRTVGRVLLLISGVWLL------SLLISSPPLIGWNDWPDEFTSATPCE 262
            ::|||.|::||:.|..:.|.......|:..|||      ||:.:.....|..|.....|....|:
Mouse   142 SVDRYIAVSDPLIYPTRFTASVSNKCITFSWLLSISYGFSLIYTGASEAGLEDLVSALTCVGGCQ 206

  Fly   263 LTSQRGYVIYSSLGSFFIPLAIMTIVYIEIFVATRRRLRERARANKLNTIALKSTELEPMANSSP 327
            |...:.:|..:.| .|.||..:|..||.:||:..:::
Mouse   207 LAVNQSWVFINFL-LFLIPTLVMITVYSKIFLIAKQQ---------------------------- 242

  Fly   328 VAASNSGSKSRLLASWLCCGRDRAQFATPMIQNDQESISSETHQPQDSSKAGPHGNSDPQQQHVV 392
              |.|.                             |.:|.:|.:..||
Mouse   243 --AQNI-----------------------------EKMSKQTARASDS----------------- 259

  Fly   393 VLVKKSRRAKTKDSIKHGKTRGGRKSQSSSTCEPHGEQQLLPAGGDGGSCQPGGGHSGGGKSDAE 457
               .|.|.||
Mouse   260 ---YKDRVAK------------------------------------------------------- 266

  Fly   458 ISTESGSDPKGCIQVCVTQADEQTSLKLTPPQSSTGVAAVSVTPLQKKTSGVNQFIEEKQKISLS 522
                                                                             
Mouse   267 ----------------------------------------------------------------- 266

  Fly   523 KERRAARTLGIIMGVFVICWLPFFLMYVILPFCQTCCPTNKFKNFITWLGYINSGLNPVIYTIFN 587
            :||:||:||||.:..|::.|||:|:...|..|.....||..:: .:.|:.|.||.:||:||..|.
Mouse   267 RERKAAKTLGIAVAAFLLSWLPYFIDSFIDAFLGFITPTYVYE-ILVWIAYYNSAMNPLIYAFFY 330

  Fly   588 LDYRRAFK 595
            ..:|:|.|
Mouse   331 PWFRKAIK 338

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oct-TyrR	NP_524419.2	7tmA_tyramine_octopamine_R-like	110..>294	CDD:320188	68/189 (36%)
		TM helix 1	111..137	CDD:320188	10/25 (40%)
		TM helix 2	144..170	CDD:320188	12/25 (48%)
		TM helix 3	182..212	CDD:320188	16/29 (55%)
		TM helix 4	224..247	CDD:320188	6/28 (21%)
		TM helix 5	266..294	CDD:320188	9/27 (33%)
		7tm_GPCRs	<519..594	CDD:475119	27/74 (36%)
		TM helix 6	528..550	CDD:410628	10/21 (48%)
		TM helix 7	562..587	CDD:410628	8/24 (33%)
Taar7e	NP_001010835.1	7tm_GPCRs	49..337	CDD:475119	107/489 (22%)
		TM helix 1	50..74	CDD:410628	10/24 (42%)
		TM helix 2	83..105	CDD:410628	12/21 (57%)
		TM helix 3	121..143	CDD:410628	11/21 (52%)
		TM helix 4	166..182	CDD:410628	4/15 (27%)
		TM helix 5	210..233	CDD:410628	7/23 (30%)
		TM helix 6	272..294	CDD:410628	10/21 (48%)
		TM helix 7	305..330	CDD:410628	9/25 (36%)