Protein Alignment Oct-TyrR and octr-1

DIOPT Version :10

• Sequence 1: NP_524419.2
• Gene: Oct-TyrR / 42452
• FlyBaseID: FBgn0004514
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: NP_001024569.1
• Gene: octr-1 / 184469
• WormBaseID: WBGene00006411
• Length: 408
• Species: Caenorhabditis elegans
• Alignment Length: 497
• Identity: 160/497 - (32%)
• Similarity: 244/497 - (49%)
• Gaps: 129/497 - (25%)

  Fly   108 EALLTALVLSVIIVLTIIGNILVILSVFTYKPLRIV-QNFFIVSLAVADLTVALLVLPFNVAYSI 171
            ||:||...:..:::|.|.||:||:::|:..:.||:. ||:.||||||||:.|.|||:|..:.|.|
 Worm    20 EAVLTISSMLTVMLLIIFGNLLVVVTVYRDRKLRMQRQNWLIVSLAVADMLVGLLVMPLTLTYEI 84

  Fly   172 LGRWEFGIHLCKLWLTCDVLCCTSSILNLCAIALDRYWAITDPINYAQKRTVGRVLLLISGVWLL 236
            :|.|..|..||::||..|||..|:|||::|||:||||:::|.|:.|...||..|:.:.|...|::
 Worm    85 VGEWTMGNILCEIWLALDVLFVTASILHICAISLDRYFSVTSPLTYPATRTPLRMFIYIGVSWIV 149

  Fly   237 SLLISSPPLIGWNDWPDEFTSATPCELTSQRGYVIYSSLGSFFIPLAIMTIVYIEIFVAT----R 297
            ||||..||:.||.  |:.  :...|.:::..|||:|||||||:||:.|:.|||.:|:..|    |
 Worm   150 SLLICLPPIFGWR--PER--AEGECSVSTDLGYVLYSSLGSFYIPVVILIIVYAKIYSITIRHSR 210

  Fly   298 RRLRE-RARANKLNTIALKSTELEPMANSSPVAASNSGSKSRLLASWLCCGRDRAQFATPMIQND 361
            :||:| ..|.:.||.:.::|:                                         .|:
 Worm   211 QRLKETERRDHTLNMLTIRSS-----------------------------------------TNE 234

  Fly   362 QESISSETHQPQDSSKAGPHGNSDPQQQHVVVLVKKSRRAKTKDSIKHGKTRGGRKSQSSSTCEP 426
            :.::..|..:           ||||.:.      :|.:....:|.|             :..|
 Worm   235 RYNMEYELEE-----------NSDPIED------EKEKVVTNRDMI-------------NKVC-- 267

  Fly   427 HGEQQLLPAGGDGGSCQPGGGHSGGGKSDAEISTESGSDPKGCIQVCVTQADEQTSLKLTPPQSS 491
               .||                       .:||.|.   |:..::|.:.......|    ||.|.
 Worm   268 ---WQL-----------------------RKISEEL---PRQGVKVSIALDTNHNS----PPASD 299

  Fly   492 TGVAAVSVTPLQKKTSGVNQFIEEKQKISLSKERRAARTLGIIMGVFVICWLPFFLMYVILPFCQ 556
            .      ...|::|     :|.|::::...:|||:|...||||:..|::.||||||:|||..|..
 Worm   300 L------TRKLEEK-----KFCEKRKRKLKAKERQATLLLGIILSAFILSWLPFFLIYVIGAFGH 353

  Fly   557 TCCPTNKFKNFITWLGYINSGLNPVIYTIFNLDYRRAFKRLL 598
            . .|...|| |..||||.|||:||||||:||.:::|...:.|
 Worm   354 E-APPLVFK-FFFWLGYCNSGINPVIYTVFNREFKRGLCKQL 393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oct-TyrR	NP_524419.2	7tmA_tyramine_octopamine_R-like	110..>294	CDD:320188	84/184 (46%)
		TM helix 1	111..137	CDD:320188	9/25 (36%)
		TM helix 2	144..170	CDD:320188	15/25 (60%)
		TM helix 3	182..212	CDD:320188	17/29 (59%)
		TM helix 4	224..247	CDD:320188	9/22 (41%)
		TM helix 5	266..294	CDD:320188	17/27 (63%)
		7tm_GPCRs	<519..594	CDD:475119	39/74 (53%)
		TM helix 6	528..550	CDD:410628	11/21 (52%)
		TM helix 7	562..587	CDD:410628	16/24 (67%)
octr-1	NP_001024569.1	7tmA_alpha2_AR	22..389	CDD:320187	157/489 (32%)
		TM helix 1	23..49	CDD:320187	9/25 (36%)
		TM helix 2	57..83	CDD:320187	15/25 (60%)
		TM helix 3	95..125	CDD:320187	17/29 (59%)
		TM helix 4	137..160	CDD:320187	9/22 (41%)
		TM helix 5	175..204	CDD:320187	17/28 (61%)
		TM helix 6	319..349	CDD:320187	17/29 (59%)
		TM helix 7	357..382	CDD:320187	16/25 (64%)