Protein Alignment Oct-TyrR and ser-4

DIOPT Version :9

• Sequence 1: NP_001163494.1
• Gene: Oct-TyrR / 42452
• FlyBaseID: FBgn0004514
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: NP_497452.1
• Gene: ser-4 / 175322
• WormBaseID: WBGene00004779
• Length: 445
• Species: Caenorhabditis elegans
• Alignment Length: 545
• Identity: 163/545 - (29%)
• Similarity: 247/545 - (45%)
• Gaps: 122/545 - (22%)

  Fly    64 EGLTTVTAALSTAQADKDSAGECEGA--VEEL--HASILGLQLAVPEWEALLTALVLSVIIVLTI 124
            |.|..:||:.|:..|...|| ...|.  |::.  ||.|.. .:..|..:.::.|.||.|:|:...
 Worm     4 ETLLNLTASPSSQPATLLSA-VARGTHLVDQFPAHAEIFS-DIERPLVQTVILASVLLVLILSCF 66

  Fly   125 IGNILVILSVFTYKPLR-IVQNFFIVSLAVADLTVALLVLPFNVAYSILGRWEFGIHLCKLWLTC 188
            |||:.|||::...:.|| ..|.:.|.|||||||.|.::|.|....:::.|.|..|:.:|..|::.
 Worm    67 IGNLFVILAIIMERDLRGRPQYYLIFSLAVADLLVGMIVTPLGAWFTVTGTWNLGVVVCDFWISV 131

  Fly   189 DVLCCTSSILNLCAIALDRYWAITDPINYAQKRTVGRVLLLISGVWLLSLLISSPPLIGWND--W 251
            |||.||:|||:|.||||||||:||| |.|.|.||..|:.|:::.:|..|||||..|..||.|  :
 Worm   132 DVLVCTASILHLVAIALDRYWSITD-ICYVQNRTPKRITLMLAVIWFTSLLISLAPFAGWKDEGF 195

  Fly   252 PDEFTSATPCELTSQRGYVIYSSLGSFFIPLAIMTIVYIEIFVATRRRLRERARANKLNTIALKS 316
            .|....:..|.::.|..|.::|:..:|:|||..:..||.:|..|.::|.:..
 Worm   196 SDRVLKSHVCLISQQISYQVFSTATAFYIPLIAIICVYWKIMRAAKKRFKRE------------- 247

  Fly   317 TELEPMANSSPVAASNSGSKSRLLASWLCCGRDRAQFATPMIQNDQESISSETHQPQDSSKAGPH 381
                                           |||    ..:|:...::|        |..||
 Worm   248 -------------------------------RDR----RTVIRPPPDAI--------DEKKA--- 266

  Fly   382 GNSDPQQQHVVVLVKKSRRAKTKDS--IKHGKTRGGRKSQSSSTCEPHGEQQLLPAGGDGGSCQP 444
                       ::.|||::.....:  |...:..||...:::|...|                 |
 Worm   267 -----------MMPKKSKKCPLPPAVVISDIQANGGTGGKTNSIKNP-----------------P 303

  Fly   445 GGGHSGGGKSDAEISTESGSDPKGCIQVCVTQADEQTSLKLTPPQSSTGVAAVSVTPLQKKTSGV 509
            ....|....|:.|.:....:...|.:....|:.||:..      :|..|:              |
 Worm   304 RHNESSSSASEEERTMTQTNHAPGDVTTQETKIDEENG------RSKPGI--------------V 348

  Fly   510 NQFIEEKQKISLSKERRAARTLGIIMGVFVICWLPFFLMYVILPFCQTCCPTNKFKNFIT-WLGY 573
            .:....|:...:.:||:|.|||.||.|.||.||.||||:.:..|.|.  |..:.....:| ||||
 Worm   349 KRRRRTKESNEMKRERKAWRTLAIITGTFVACWTPFFLVSIYRPICG--CQISPVLEQVTLWLGY 411

  Fly   574 INSGLNPVIYTIFNLDYRRAFKRLL 598
            :||.|||:|||:|:.|:|.||||::
 Worm   412 LNSALNPIIYTVFSQDFRAAFKRII 436

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oct-TyrR	NP_001163494.1	Zinc_peptidase_like	<113..244	CDD:301362	63/131 (48%)
		7tm_1	126..>293	CDD:278431	72/169 (43%)
ser-4	NP_497452.1	7tmA_5-HT1A_invertebrates	52..432	CDD:320454	145/489 (30%)
		TM helix 1	53..79	CDD:320454	11/25 (44%)
		TM helix 2	87..113	CDD:320454	12/25 (48%)
		TM helix 3	125..155	CDD:320454	19/29 (66%)
		TM helix 4	166..188	CDD:320454	9/21 (43%)
		TM helix 5	210..239	CDD:320454	10/28 (36%)
		TM helix 6	361..391	CDD:320454	17/29 (59%)
		TM helix 7	400..425	CDD:320454	13/24 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BCYC
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002041
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_104614
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.710