Protein Alignment Oct-TyrR and Oct-TyrR

DIOPT Version :10

• Sequence 1: NP_524419.2
• Gene: Oct-TyrR / 42452
• FlyBaseID: FBgn0004514
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: XP_061506991.1
• Gene: Oct-TyrR / 1273444
• VectorBaseID: AGAMI1_002266
• Length: 644
• Species: Anopheles gambiae
• Alignment Length: 633
• Identity: 328/633 - (51%)
• Similarity: 386/633 - (60%)
• Gaps: 131/633 - (20%)

  Fly    64 EG-LTTVTAALSTAQADKDSAGECEGA-------------------VEELHASILGLQLAVPEWE 108
            || :..|:.|..||....||.||..||                   .:.|:.::.|:.||||:||
Mosquito    45 EGSIPAVSLAGLTATLGLDSNGELLGANYGANGSDLSELLDGCPKPDDTLYPTMFGIDLAVPQWE 109

  Fly   109 ALLTALVLSVIIVLTIIGNILVILSVFTYKPLRIVQNFFIVSLAVADLTVALLVLPFNVAYSILG 173
            |:.|||:|::||::||:||||||||||||||||||||||||||||||||||:||||.|||||:||
Mosquito   110 AIGTALILTLIIIITIVGNILVILSVFTYKPLRIVQNFFIVSLAVADLTVAILVLPLNVAYSLLG 174

  Fly   174 RWEFGIHLCKLWLTCDVLCCTSSILNLCAIALDRYWAITDPINYAQKRTVGRVLLLISGVWLLSL 238
            |||||||:||:|||.||||||:|||||||||||||||||||||||||||:.|||.||:|||:|||
Mosquito   175 RWEFGIHVCKMWLTSDVLCCTASILNLCAIALDRYWAITDPINYAQKRTLERVLALIAGVWVLSL 239

  Fly   239 LISSPPLIGWNDWPDEFTSATPCELTSQRGYVIYSSLGSFFIPLAIMTIVYIEIFVATRRRLRER 303
            :|||||||||||||:||:|..||:|||.:|||||||||||||||||||||||||::|||||||||
Mosquito   240 VISSPPLIGWNDWPEEFSSEFPCQLTSNQGYVIYSSLGSFFIPLAIMTIVYIEIYIATRRRLRER 304

  Fly   304 ARANKLNTIALKSTELEPMANSSPVAASNSGSKSRLLASWLCCGRDRAQFATPM----------- 357
            |:|:|:||:|.:|..:          .:.:|.|.      |.....:.|.....
Mosquito   305 AQASKINTLASRSIGM----------VAGNGEKE------LTTTHHQQQQQQQQHQHHHQSHHHQ 353

  Fly   358 ----IQNDQESISSET--HQPQ-DSSKAGP--HGNSDPQQQHVVVLVKKSRRAKTKDSIKHGKTR 413
                ||:|||||||||  |..| |:...||  .|:..|.::..:.......||....:.:|.|.:
Mosquito   354 DGHAIQHDQESISSETNNHNEQTDTGSGGPVLAGSGKPNKKGHLRFGGYLGRALGGAAGRHRKKQ 418

  Fly   414 GGRKSQSSSTCE------PH--GEQQLLPAGGDGGSCQP---GGGHSGGGKSDAEISTESGSDPK 467
            ..||.......|      ||  ....|.....|..:..|   |.|.||||...|.:.....|
Mosquito   419 HHRKRPGDGPAEEGEDGRPHRLAASALHQREDDSVTDNPDHSGSGDSGGGVGKAPLDAAHPS--- 480

  Fly   468 GCIQVCVTQADEQTSLKLTPPQ--------SSTG---------------------------VAAV 497
                            .|.||.        |:||                           |.|.
Mosquito   481 ----------------ALLPPTGNCDMTGGSATGEPAPRNGASNNHHQREVGFHESTAELMVVAA 529

  Fly   498 SVTPLQ----------KKTSGVNQFIEEKQKISLSKERRAARTLGIIMGVFVICWLPFFLMYVIL 552
            :..|..          :|..|:||||||||||||||||||||||||||||||:||||||||||||
Mosquito   530 AAPPTTRLGGRLKQSFRKPGGINQFIEEKQKISLSKERRAARTLGIIMGVFVVCWLPFFLMYVIL 594

  Fly   553 PFCQTCCPTNKFKNFITWLGYINSGLNPVIYTIFNLDYRRAFKRLLGL 600
            |||.:||||||..|||||||||||.|||:||||||||||||||||||:
Mosquito   595 PFCPSCCPTNKLINFITWLGYINSALNPIIYTIFNLDYRRAFKRLLGI 642

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oct-TyrR	NP_524419.2	7tmA_tyramine_octopamine_R-like	110..>294	CDD:320188	155/183 (85%)
		TM helix 1	111..137	CDD:320188	18/25 (72%)
		TM helix 2	144..170	CDD:320188	23/25 (92%)
		TM helix 3	182..212	CDD:320188	26/29 (90%)
		TM helix 4	224..247	CDD:320188	17/22 (77%)
		TM helix 5	266..294	CDD:320188	25/27 (93%)
		7tm_GPCRs	<519..594	CDD:475119	67/74 (91%)
		TM helix 6	528..550	CDD:410628	20/21 (95%)
		TM helix 7	562..587	CDD:410628	20/24 (83%)
Oct-TyrR	XP_061506991.1	None