Protein Alignment Oct-TyrR and AdoR

DIOPT Version :10

• Sequence 1: NP_524419.2
• Gene: Oct-TyrR / 42452
• FlyBaseID: FBgn0004514
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: XP_310647.2
• Gene: AdoR / 1271793
• VectorBaseID: AGAMI1_006181
• Length: 392
• Species: Anopheles gambiae
• Alignment Length: 490
• Identity: 113/490 - (23%)
• Similarity: 176/490 - (35%)
• Gaps: 179/490 - (36%)

  Fly   113 ALVLSVIIVLTIIGNILVILSVFTYKPLRIVQNFFIVSLAVADLTVALLVLPFNVAYSI-LGRWE 176
            ||:.:.:.::.|.||.|||::..|.:.||...|::|||||.|||.|..|.:||.|..|| |.|
Mosquito    44 ALLEATVALMAIFGNTLVIVAFRTERRLRRRTNYYIVSLASADLLVGTLGIPFAVLASIGLPR-- 106

  Fly   177 FGIHLCKLWLTCDVLCCTSSILNLCAIALDRYWAITDPINYAQKRTVGRVLLLISGVWLLSLLIS 241
             .:|.|...::..|:.||.||..|.|:::||||||..|:.|::.......|.:||..||...::.
Mosquito   107 -NLHACLFTISLLVVLCTISIFCLVAVSIDRYWAILHPLAYSRNMRTKTTLYIISMCWLAGFIVG 170

  Fly   242 SPPLIGWNDWPDEFTSATPCELTSQRGYVIYSSLGSFFIPLAIMTIVYIEIFVATRRRLRERARA 306
            ..||.||::.|.|  .|..........|:::..|.:..||..::...||.|:   |..:|:|.:.
Mosquito   171 FLPLFGWHEQPAE--DACLFVKVMNYDYLVFLYLVTIIIPAVLLLAFYIHIY---RVIVRQRKQI 230

  Fly   307 NKLNTIALKSTELEPMANSSPVAASNSGSKSRLLASWLCCGRDRAQFATPMIQNDQESISSETHQ 371
            ..:|:|                       .||.:|
Mosquito   231 LSVNSI-----------------------DSRCMA------------------------------ 242

  Fly   372 PQDSSKAGPHGNSDPQQQHVVVLVKKSRRAKTKDSIKHGKTRGGRKSQSSSTCEPHGEQQLLPAG 436
                                              ||:.|.
Mosquito   243 ----------------------------------SIEDGT------------------------- 248

  Fly   437 GDGGSCQPGGGHSGGGKSDAEISTESGSDPKGCIQVCVTQADEQ---TSLKLTPPQSSTGVAAVS 498
               |||...|.|:...:                     ||..:|   |.|::.
Mosquito   249 ---GSCSQSGRHATKRR---------------------TQRKDQYSGTMLRVL------------ 277

  Fly   499 VTPLQKKTSGVNQFIEEKQKISLSKERRAARTLGIIMGVFVICWLPFFLMYVILPFCQTCCPTNK 563
                               :.:.::|.:|.:.|.||:..|::||:|...:..|:.||..|.....
Mosquito   278 -------------------RAAQNREVKATQNLSIIVLFFMLCWMPLHTINCIVAFCPQCHIHAP 323

  Fly   564 FKNFITWLGYINSGLNPVIYTIFNLDYRRAFKRLL 598
            ....:..|.::||.|||::|.....|:|.|.||||
Mosquito   324 VMLLVITLSHLNSALNPLLYAYHLKDFRAALKRLL 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oct-TyrR	NP_524419.2	7tmA_tyramine_octopamine_R-like	110..>294	CDD:320188	65/181 (36%)
		TM helix 1	111..137	CDD:320188	8/23 (35%)
		TM helix 2	144..170	CDD:320188	14/25 (56%)
		TM helix 3	182..212	CDD:320188	13/29 (45%)
		TM helix 4	224..247	CDD:320188	7/22 (32%)
		TM helix 5	266..294	CDD:320188	7/27 (26%)
		7tm_GPCRs	<519..594	CDD:475119	22/74 (30%)
		TM helix 6	528..550	CDD:410628	7/21 (33%)
		TM helix 7	562..587	CDD:410628	7/24 (29%)
AdoR	XP_310647.2	None