Protein Alignment Oct-TyrR and LOC1269968

DIOPT Version :10

• Sequence 1: NP_524419.2
• Gene: Oct-TyrR / 42452
• FlyBaseID: FBgn0004514
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: XP_061499186.1
• Gene: LOC1269968 / 1269968
• VectorBaseID: AGAMI1_010361
• Length: 587
• Species: Anopheles gambiae
• Alignment Length: 624
• Identity: 183/624 - (29%)
• Similarity: 273/624 - (43%)
• Gaps: 159/624 - (25%)

  Fly    44 SDDDAGMGTEAVANISGSLVEGLT---TVTAALSTAQADKDSAGECEGAVEELHASILGLQLAVP 105
            |.|...:|.|...|.|.:.....|   .|.|:::             |..:|..|.::.:
Mosquito    40 SADVGSIGNETFFNESANAFANTTDLGPVPASIN-------------GTADEPLADVIVM----- 86

  Fly   106 EWEALLTALVLSVIIVLTIIGNILVILSVFTYKPLRIVQNFFIVSLAVADLTVALLVLPFNVAYS 170
                .:|:|||.::|::|:|||:.||.::...:.|:.|.|:.:.|||||||.||.||:|....|.
Mosquito    87 ----AITSLVLGLMILVTVIGNVFVIAAIILERNLQNVANYLVASLAVADLFVACLVMPLGAVYE 147

  Fly   171 ILGRWEFGIHLCKLWLTCDVLCCTSSILNLCAIALDRYWAITDPINYAQKRTVGRVLLLISGVWL 235
            |...|..|..||.:|.:|||||||:|||:|.|||.|||||:|: |:|...||..||..:|..||.
Mosquito   148 ISRGWILGPELCDIWTSCDVLCCTASILHLVAIATDRYWAVTN-IDYIHSRTSRRVFTMIFLVWF 211

  Fly   236 LSLLISSPPLIGWNDWPD--EFTSATPCELTSQRGYVIYSSLGSFFIPLAIMTIVYIEIFVATRR 298
            .|:::|..|..||.| |:  :......|.::....|.::::..:|::||.::.::|.:|:...||
Mosquito   212 ASVIVSLAPQFGWKD-PEYLQRIEQQKCMVSQNIAYQVFATCCTFYVPLFVILVLYWKIYQTARR 275

  Fly   299 RLRER--------------------------------------------ARANKLNTIALKSTEL 319
            |:..|                                            ...|..||:    ..:
Mosquito   276 RIHRRGPKIPATPNSSNQEETPKPKSKIRFHLKKKFTNPTKSAVSSLGLVEGNSTNTV----NTV 336

  Fly   320 EPMANSSPVAASNSGSKSRLLASWLCCGRDRAQFATPMIQNDQESISSE-THQPQDSSKAG---P 380
            |...:|:..||...|.::..       ..|... .||:..|...::|.| ||| |.:..||   .
Mosquito   337 EDTEDSTANAADRKGLETTF-------SGDEGN-GTPLGNNQIPTVSYEVTHQ-QLAQAAGCSES 392

  Fly   381 HGNSDPQQQHVVVLVKKSRRAKTKDSIKHGKTRGG----RKSQSSSTCEPHGEQQ-------LLP 434
            :.|::|.        :.....||..|...|...|.    :...:||...|...|.       ..|
Mosquito   393 NNNNNPG--------RTGSAGKTSPSGNGGTLPGSTYPVQAVHASSPLLPPQHQHHNAATAAKQP 449

  Fly   435 AGGDGGSCQPGGGHSG----GGKSDAEISTESGSDPKGCIQVCVTQADEQTSLKLTP-PQSSTGV 494
            ||.......||...||    ||.|...|::                         || ||:
Mosquito   450 AGTPTAHLTPGSAGSGLQGAGGGSTLNIAS-------------------------TPNPQA---- 485

  Fly   495 AAVSVTPLQKKTSGVNQFIEEKQKISLSKERRAARTLGIIMGVFVICWLPFFLMYVILPFCQTCC 559
                            |..:.|:.:...:||:||:||.||.|.||:|||||||..::||.|::|.
Mosquito   486 ----------------QVSKRKETLEAKRERKAAKTLAIITGAFVVCWLPFFLTALLLPLCESCS 534

  Fly   560 PTNKFKNFITWLGYINSGLNPVIYTIFNLDYRRAFKRLL 598
            ..:...:...||||.||.|||||||||:.::|:||||:|
Mosquito   535 INDTVASLFLWLGYFNSTLNPVIYTIFSPEFRQAFKRIL 573

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oct-TyrR	NP_524419.2	7tmA_tyramine_octopamine_R-like	110..>294	CDD:320188	76/185 (41%)
		TM helix 1	111..137	CDD:320188	11/25 (44%)
		TM helix 2	144..170	CDD:320188	13/25 (52%)
		TM helix 3	182..212	CDD:320188	21/29 (72%)
		TM helix 4	224..247	CDD:320188	8/22 (36%)
		TM helix 5	266..294	CDD:320188	6/27 (22%)
		7tm_GPCRs	<519..594	CDD:475119	38/74 (51%)
		TM helix 6	528..550	CDD:410628	15/21 (71%)
		TM helix 7	562..587	CDD:410628	14/24 (58%)
LOC1269968	XP_061499186.1	None