Protein Alignment Oct-TyrR and htr7

DIOPT Version :10

• Sequence 1: NP_524419.2
• Gene: Oct-TyrR / 42452
• FlyBaseID: FBgn0004514
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: XP_003199632.2
• Gene: htr7 / 100536080
• -ID: -
• Length: 410
• Species: Danio rerio
• Alignment Length: 514
• Identity: 140/514 - (27%)
• Similarity: 210/514 - (40%)
• Gaps: 193/514 - (37%)

  Fly    99 GLQLAVP-----EWEALLTALVLSVIIVLTIIGNILVILSVFTYKPLRIVQNFFIVSLAVADLTV 158
            |.:..||     ..|.:|...||:::..||:.||:||::||...|.|:...|:.|||||||||:|
Zfish    46 GTRCGVPILSYGHVEKVLIGGVLTMLTFLTVCGNLLVVISVCFVKKLKQPSNYLIVSLAVADLSV 110

  Fly   159 ALLVLPF-NVAYSILGRWEFGIHLCKLWLTCDVLCCTSSILNLCAIALDRYWAITDPINYAQKRT 222
            |::|:|| ::...|.|:|.||...|.:::..||:|||:||:.||.|::|||..||.|:.|..:::
Zfish   111 AVVVMPFVSITDLIGGQWIFGRVFCNVFIAMDVMCCTASIMTLCVISIDRYLGITKPLTYPVRQS 175

  Fly   223 VGRVLLLISGVWLLSLLISSPPLIGW----NDWPDEFTSATPCELTSQRGYVIYSSLGSFFIPLA 283
            ...:..::..|||||..|:.|||.||    ||       ...|.::...||.|||:..:|:||::
Zfish   176 GKCMAKIVLSVWLLSASITLPPLFGWAQNVND-------DNVCLISQDLGYTIYSTAVAFYIPMS 233

  Fly   284 IMTIVYIEIFVATRRRLRERARANKLNTIALKSTELEPMANSSPVAASNSGSKSRLLASWLCCGR 348
            :|.|:|..|:     |:.:.:.|.  :|||                                 |.
Zfish   234 VMLIMYYRIY-----RVAKDSAAK--HTIA---------------------------------GF 258

  Fly   349 DRAQFATPMIQNDQESISSETHQPQDSSKAGPHGNSDPQQQHVVVLVKKSRRAKTKDSIKHGKTR 413
            .:|:        |:||::
Zfish   259 PKAE--------DEESMN----------------------------------------------- 268

  Fly   414 GGRKSQSSSTCEPHGEQQLLPAGGDGGSCQPGGGHSGGGKSDAEISTESGSDPKGCIQVCVTQAD 478
                                                                       |||.|
Zfish   269 -----------------------------------------------------------CVTAA- 273

  Fly   479 EQTSLKLTPPQSSTGVAAVSVTPLQKKTSGVNQFIEEKQKISLSK-ERRAARTLGIIMGVFVICW 542
                |||......    .||.:.|.|         .:::.||:.| |::||.||||::|.|.:||
Zfish   274 ----LKLQREVEE----CVSFSRLLK---------SDRKNISIFKREQKAAATLGIVVGAFAVCW 321

  Fly   543 LPFFLMYVILPF-C--QTCCPTNKFKNFITWLGYINSGLNPVIYTIFNLDYRRAFKRLL 598
            :||||:....|| |  |..|.....:..:.||||.||.:||.||..||.|.|..:..|:
Zfish   322 MPFFLLSTARPFICGLQCSCVPLWVERTLLWLGYANSLINPFIYAFFNRDLRTTYHNLI 380

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oct-TyrR	NP_524419.2	7tmA_tyramine_octopamine_R-like	110..>294	CDD:320188	77/188 (41%)
		TM helix 1	111..137	CDD:320188	11/25 (44%)
		TM helix 2	144..170	CDD:320188	15/26 (58%)
		TM helix 3	182..212	CDD:320188	14/29 (48%)
		TM helix 4	224..247	CDD:320188	9/22 (41%)
		TM helix 5	266..294	CDD:320188	12/27 (44%)
		7tm_GPCRs	<519..594	CDD:475119	37/78 (47%)
		TM helix 6	528..550	CDD:410628	13/21 (62%)
		TM helix 7	562..587	CDD:410628	10/24 (42%)
htr7	XP_003199632.2	7tmA_5-HT7	62..376	CDD:320452	135/492 (27%)
		TM helix 1	63..89	CDD:320452	11/25 (44%)
		TM helix 2	96..122	CDD:320452	15/25 (60%)
		TM helix 3	135..165	CDD:320452	14/29 (48%)
		TM helix 4	177..199	CDD:320452	8/21 (38%)
		TM helix 5	216..245	CDD:320452	12/33 (36%)
		TM helix 6	301..331	CDD:320452	16/29 (55%)
		TM helix 7	344..369	CDD:320452	10/24 (42%)