Protein Alignment Oct-TyrR and htr1d

DIOPT Version :9

• Sequence 1: NP_001163494.1
• Gene: Oct-TyrR / 42452
• FlyBaseID: FBgn0004514
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: XP_002938881.3
• Gene: htr1d / 100494760
• XenbaseID: XB-GENE-992184
• Length: 376
• Species: Xenopus tropicalis
• Alignment Length: 523
• Identity: 146/523 - (27%)
• Similarity: 235/523 - (44%)
• Gaps: 168/523 - (32%)

  Fly    81 DSAGECEGAVEELHASILGLQLAVPEWEALLTALVLSVIIVLTIIGNILVILSVFTYKPLRIVQN 145
            :|....:..:.:..:::|||::|:        |::||:|.:.|::.|:.||:::...:.|....|
 Frog    17 ESLNSSDIMIGQEESTLLGLKIAL--------AVLLSIITLATLLSNVFVIITIVMTRKLHTPAN 73

  Fly   146 FFIVSLAVADLTVALLVLPFNVAYSILGRWEFGIHLCKLWLTCDVLCCTSSILNLCAIALDRYWA 210
            :.|.|||..||.|::||:|.::||::...|.||..:|.:||..|:.|||:|||:||.||||||||
 Frog    74 YLIGSLAFTDLLVSILVMPISIAYTVTHTWTFGQIVCDIWLLSDITCCTASILHLCVIALDRYWA 138

  Fly   211 ITDPINYAQKRTVGRVLLLISGVWLLSLLISSPPLIGWNDWPDEFTSATPCEL-TSQRGYVIYSS 274
            |||.:.|.:.||..|..::|..||::|:.||.|||. |.. .......|.|.: |.|..|.|||:
 Frog   139 ITDALEYTKHRTARRAAVMILVVWIISICISIPPLF-WRQ-AKAHEELTVCTINTDQISYTIYST 201

  Fly   275 LGSFFIPLAIMTIVYIEIFVATRRRLRERARANKLNTIALKSTELEPMANSSPVAASNSGSKSRL 339
            .|:|:||..::.::|.:|::|.|.|:                  |:|        .|..|  .|.
 Frog   202 CGAFYIPTVLLILLYGKIYIAARSRI------------------LKP--------PSIYG--KRF 238

  Fly   340 LASWLCCGRDRAQFATPMIQNDQESISSETHQPQDSSKAGPHGNSDPQQQHVVVLVKKSRRAKTK 404
            ..:.|..|...:.|.         ||::..|...      ||.:..|
 Frog   239 TTAQLITGSTGSSFC---------SINANVHMEH------PHTSETP------------------ 270

  Fly   405 DSIKHGKTRGGRKSQSSSTCEPHGEQQLLPAGGDGGSCQPGGGHSGGGKSDAEISTESGSDPKGC 469
                                                                             
 Frog   271 ----------------------------------------------------------------- 270

  Fly   470 IQVCVTQADEQTSLKLTPPQSSTGVAAVSVTPLQKKTSGVNQFIEEKQKISLSKERRAARTLGII 534
              ||:    ....:||.                        ..|.|::::|.::|::|.:|||||
 Frog   271 --VCI----NHIKIKLA------------------------DSIIERKRLSAAREKKATKTLGII 305

  Fly   535 MGVFVICWLPFFLMYVILPFCQTCCPTNKFK-NFITWLGYINSGLNPVIYTIFNLDYRRAFKRLL 598
            :|.|::||||||::.::||.|:..|..:... :|.|||||:||.:||||||:||.|:::||::|:
 Frog   306 LGAFIVCWLPFFVVSLVLPICRDACWFDPLLFDFFTWLGYLNSLINPVIYTVFNEDFKKAFQKLI 370

  Fly   599 GLN 601
            .||
 Frog   371 RLN 373

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oct-TyrR	NP_001163494.1	Zinc_peptidase_like	<113..244	CDD:301362	58/130 (45%)
		7tm_1	126..>293	CDD:278431	70/167 (42%)
htr1d	XP_002938881.3	7tmA_5-HT1B_1D	34..366	CDD:320455	140/497 (28%)
		TM helix 1	40..64	CDD:320455	8/31 (26%)
		TM helix 2	73..95	CDD:320455	11/21 (52%)
		TM helix 3	111..133	CDD:320455	12/21 (57%)
		TM helix 4	156..172	CDD:320455	6/15 (40%)
		TM helix 5	194..217	CDD:320455	8/22 (36%)
		TM helix 6	299..321	CDD:320455	13/21 (62%)
		TM helix 7	334..359	CDD:320455	14/24 (58%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H20240
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.000