Protein Alignment Oct-TyrR and LOC100490372

DIOPT Version :10

• Sequence 1: NP_524419.2
• Gene: Oct-TyrR / 42452
• FlyBaseID: FBgn0004514
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: XP_002937327.2
• Gene: LOC100490372 / 100490372
• XenbaseID: XB-GENE-29080159
• Length: 405
• Species: Xenopus tropicalis
• Alignment Length: 543
• Identity: 130/543 - (23%)
• Similarity: 206/543 - (37%)
• Gaps: 229/543 - (42%)

  Fly    85 ECEG------------AVEELHASILGLQLAVPEWEALLTAL-----------VLSVIIVLTIIG 126
            ||:|            ::::..:|:.....:....|...|||           :|:||.::|.:|
 Frog     8 ECQGVGMASGQSRLKMSMDKNVSSLCNFSFSFLRREGNRTALEIAPQQVAVGSLLTVIDLITFLG 72

  Fly   127 NILVILSVFTYKPLRIVQNFFIVSLAVADLTVALLVLPFNVAYSILGRWEFGIHLCKLWLTCDVL 191
            |.:|.:.....|.||.|...||:|||:|||.||.||:||::.|.:.|.|.||...||:|::.||:
 Frog    73 NAVVFICPVVEKRLRTVTYMFIMSLAMADLLVACLVMPFSIIYEVTGMWLFGKQFCKVWISFDVM 137

  Fly   192 CCTSSILNLCAIALDRYWAITDPINYAQKRTVGRVLLLISGVWLLSLLISSPPLI-GWNDWPDEF 255
            .||:||:.||.|:||||.::..|.:|:::.:..|.:::...:|:.|.|||..|:: |||:.|...
 Frog   138 FCTASIVTLCFISLDRYCSVVTPYHYSKRMSRRRCIIMTVTIWVYSSLISFLPVMQGWNEIPGVD 202

  Fly   256 T-SATPCELTSQRGYVIYSSLGSFFIPLAIMTIVYIEIFVATRRRLRERARANKLNTIALKSTEL 319
            | :...|...:...:.|.:|..:|:||..||..:|..|:.|:|                ||:|
 Frog   203 TDNGKQCIFVTNWTFAIVASSLAFYIPFIIMCSMYFFIYRASR----------------LKAT-- 249

  Fly   320 EPMANSSPVAASNSGSKSRLLASWLCCGRDRAQFATPMIQNDQESISSETHQPQDSSKAGPHGNS 384
                              |:::..|                       :.|.         |.||
 Frog   250 ------------------RIVSQTL-----------------------DLHY---------HPNS 264

  Fly   385 DPQQQHVVVLVKKSRRAKTKDSIKHGKTRGGRKSQSSSTCEPHGEQQLLPAGGDGGSCQPGGGHS 449
                                                                             
 Frog   265 ----------------------------------------------------------------- 264

  Fly   450 GGGKSDAEISTESGSDPKGCIQVCVTQADEQTSLKLTPPQSSTGVAAVSVTPLQKKTSGVNQFIE 514
                                                                             
 Frog   265 ----------------------------------------------------------------- 264

  Fly   515 EKQKISLSKERRAARTLGIIMGVFVICWLPFFLMYVILPFCQTCCPT----NKFKNFITWLGYIN 575
             |::.:|..|.:|.||:|||:.|||:||||:|::.|::....|...:    |.|| |||||||.|
 Frog   265 -KRQNNLQLENKATRTMGIIISVFVMCWLPYFVLNVLIAAKGTDSTSRVLVNAFK-FITWLGYCN 327

  Fly   576 SGLNPVIYTIFNLDYRRAFKRLL 598
            |.:||::|...|.|::||.|:||
 Frog   328 STINPMLYAFLNRDFQRALKKLL 350

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oct-TyrR	NP_524419.2	7tmA_tyramine_octopamine_R-like	110..>294	CDD:320188	73/196 (37%)
		TM helix 1	111..137	CDD:320188	10/36 (28%)
		TM helix 2	144..170	CDD:320188	14/25 (56%)
		TM helix 3	182..212	CDD:320188	16/29 (55%)
		TM helix 4	224..247	CDD:320188	7/23 (30%)
		TM helix 5	266..294	CDD:320188	9/27 (33%)
		7tm_GPCRs	<519..594	CDD:475119	36/78 (46%)
		TM helix 6	528..550	CDD:410628	13/21 (62%)
		TM helix 7	562..587	CDD:410628	15/24 (63%)
LOC100490372	XP_002937327.2	7tmA_amine_R-like	58..346	CDD:320098	118/487 (24%)
		TM helix 1	58..83	CDD:320098	7/24 (29%)
		TM helix 2	90..117	CDD:320098	15/26 (58%)
		TM helix 3	128..158	CDD:320098	16/29 (55%)
		TM helix 4	170..190	CDD:320098	6/19 (32%)
		TM helix 5	214..270	CDD:320098	21/254 (8%)
		TM helix 6	271..301	CDD:320098	16/29 (55%)
		TM helix 7	311..339	CDD:320098	15/28 (54%)