Protein Alignment Oct-TyrR and drd4

DIOPT Version :10

• Sequence 1: NP_524419.2
• Gene: Oct-TyrR / 42452
• FlyBaseID: FBgn0004514
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: XP_002937535.2
• Gene: drd4 / 100486482
• XenbaseID: XB-GENE-990215
• Length: 414
• Species: Xenopus tropicalis
• Alignment Length: 343
• Identity: 67/343 - (19%)
• Similarity: 123/343 - (35%)
• Gaps: 84/343 - (24%)

  Fly   713 MPENSTDNCVSDKKEMKETS--LRISSLSEMAPRDVTSHTEAALESESSSFNSMSVAAETNQYSG 775
            :|:::.| .|.....::|.:  ||..|:.::.|:.:....:..|...|....|:|:....
 Frog    12 LPQSAGD-LVRAHPPLEERARLLRGQSVQQVGPQGLLYVQQRELAVTSPKDGSISILGSD----- 70

  Fly   776 ELLDLADAYNIVVGNEGHYDSNGRQQIENWMKKDTSRVSEDLKALLTQISASRGIEFLSPRDVSP 840
               |....:.:|:.:.|    ||...:.:....||       ||.:..|..|  |:..|......
 Frog    71 ---DATTCHIVVLRHTG----NGATCLTHCDGTDT-------KAEVPLIMNS--IKSFSDHAQCG 119

  Fly   841 KISVN-----SSDQE-TKNLDHDMQLLLQKRMLERNESNLSLEGVSVTEIEGESEGDRLKRQVDY 899
            ::.|:     |.|:: ::.|.|  |||.:   .:|.|.::.|..:.|||:....|.:. ...|.|
 Frog   120 RLEVHLVGGFSDDRQLSQKLTH--QLLSE---FDRQEDDIHLVTLCVTELNDREENEN-HFPVIY 178

  Fly   900 DRKLLTGLYKELEEERSASAVATNQAMAMITR--LQEEKASFQMEALQNLRMMEEQAEYDMEAIQ 962
                               .:|.|...|.|.|  .|:.....|:.|.:.|......:.||.|..|
 Frog   179 -------------------GIAVNIKTAEIYRASFQDRGPEEQLRAARTLAGGPMISIYDAETEQ 224

  Fly   963 -RLND------------LLVEREKLIQDLEAE--------IEYFRD------QTPQKKNKLDVAE 1000
             |:..            |..:.::::::|...        :|:.|.      :.|...:.|....
 Frog   225 LRIGPYSWTPFPHVDFWLHQDDKQILENLSTSPLAEPPHFVEHIRSTLMFLKKHPSPAHTLFSGN 289

  Fly  1001 KVTEMDSPSEGMSNKIQS 1018
            |........:|:..||.|
 Frog   290 KALLYKKNEDGLWEKISS 307

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oct-TyrR	NP_524419.2	7tmA_tyramine_octopamine_R-like	110..>294	CDD:320188
		TM helix 1	111..137	CDD:320188
		TM helix 2	144..170	CDD:320188
		TM helix 3	182..212	CDD:320188
		TM helix 4	224..247	CDD:320188
		TM helix 5	266..294	CDD:320188
		7tm_GPCRs	<519..594	CDD:475119
		TM helix 6	528..550	CDD:410628
		TM helix 7	562..587	CDD:410628
drd4	XP_002937535.2	7tmA_D4_dopamine_R	63..406	CDD:320434	57/291 (20%)
		TM helix 1	64..90	CDD:320434	6/37 (16%)
		TM helix 2	97..123	CDD:320434	8/34 (24%)
		TM helix 3	136..166	CDD:320434	11/34 (32%)
		TM helix 4	178..201	CDD:320434	7/41 (17%)
		TM helix 5	217..246	CDD:320434	6/28 (21%)
		TM helix 6	334..364	CDD:320434
		TM helix 7	374..399	CDD:320434