Protein Alignment Nep4 and ece2b

DIOPT Version :9

• Sequence 1: NP_650904.3
• Gene: Nep4 / 42449
• FlyBaseID: FBgn0038818
• Length: 1040
• Species: Drosophila melanogaster
• Sequence 2: XP_017206531.1
• Gene: ece2b / 793465
• ZFINID: ZDB-GENE-131120-140
• Length: 794
• Species: Danio rerio
• Alignment Length: 1000
• Identity: 310/1000 - (31%)
• Similarity: 460/1000 - (46%)
• Gaps: 261/1000 - (26%)

  Fly    92 MRDLRNSHS-------------EVPVYMEDYEALLPEGSTYNDLINEEF-------ILPASKRTQ 136
            ::||||:.|             :|||          :|:...|.:...|       ..|..:|||
Zfish     5 LQDLRNNMSNYKRATFEEEDGTDVPV----------DGAISPDSVEVGFRKGGIQLFGPLGRRTQ 59

  Fly   137 LQILAAERARRCQPYRYGNGESMELEERNTLMKDSRTSFLPLGIPRECLGSGIELDIKPIDEEAY 201
            |:::.|                      ..|:    .|.|.|      .|..:.|.::      |
Zfish    60 LEVVLA----------------------GLLL----ASLLAL------FGCAVTLGVR------Y 86

  Fly   202 QRQKKRYQDIAPYWLEKIRIRERREAERHAEEASAEISEATAALQSFWNEEGTREGIRMTQAKTM 266
            .|...|                           |..::||.                 :|.|..:
Zfish    87 NRDPAR---------------------------SICLTEAC-----------------VTVASKI 107

  Fly   267 KRYMDNKVDPCVDFYKYACGNWERLHPIPKDKAGFDTFEMLRESLDLVLRNLLEKNTPVHSAAEL 331
            ...:|...|||.|||:||||.|.|.:|:|..::.:.||..:.:....||::|||
Zfish   108 VEALDRSADPCQDFYQYACGGWVRKNPLPDGRSRWSTFNSIWDQNQAVLKHLLE----------- 161

  Fly   332 RKSPVRNTLFKLNEQGEGEGEADQAAELTAERLRRHIVSKRQLLNRVLVRYKRYTNGTKRKRLIE 396
                                                                   |||
Zfish   162 -------------------------------------------------------NGT------- 164

  Fly   397 TPRERTKEEEAAPPVVLPKDKTKDKSDNEEQLHVPTDFLKPHQDAQLKAKNLYRSCVNSAVLAKR 461
                                                  .....:|:.|.::.|.||:|...:.:.
Zfish   165 --------------------------------------FNSSSEAERKTQSYYLSCLNEQRIEEL 191

  Fly   462 GLEPLHTLIRELGGWPVLESQWSESNFNWQVLAATLRRYNNDILIVQWVGADIKNSEENIVQFDQ 526
            |.:||..||.::|||.:.|| |.:.|| ..||......|.........|..|.|||..|::|.||
Zfish   192 GAQPLMDLITKIGGWNITES-WDKENF-LDVLKIISGPYRAQPFFTVSVSVDPKNSNSNVIQVDQ 254

  Fly   527 TGLGLPTREYFLQPSNAKYLQAYQRYMAEVMHKMGASKADAQRVASELVAFETQLAGITAPAEQR 591
            :||.||:|:|:|..:|.|.|:||..||.|:...:|..|...:....:::.|||.||.||.|.::|
Zfish   255 SGLFLPSRDYYLNKTNEKVLKAYLDYMVELGLLLGGDKNSTRGQMQQILDFETALANITVPQDER 319

  Fly   592 LNVTKLYKRMTLDQLQAVVPEIKWRAYLQS-LQDREVLGTEEVVIYAVEYMSKLVTLLDETDPRT 655
            .:..|:|.::|:..||.:.|.|:|..||.| |...|:..||.||:||.|||.::..|:::||...
Zfish   320 RDEEKIYHKITIADLQVLAPAIEWLDYLNSVLSPLELNDTEPVVVYAKEYMQQVSELINKTDHSL 384

  Fly   656 VSNYMMWRFVRHRINNVDDRFDDIKQSFYHALFGREES-PQRWKVCIAQVNTNMGMAVGSMFVSR 719
            ::|||:|..|:...:::|.||::.:.....:|:|.::| ..||:.||...:..:|.|:|::||..
Zfish   385 LNNYMIWNLVQKGASSLDQRFENAQDKLLESLYGTKKSCTPRWQTCIGNTDDTLGFALGALFVKA 449

  Fly   720 YFDNNSKRDTLR-----------------------------MTHDLQQAFRDILKTTDWLDDTTK 755
            .||..||...|.                             |.::::.||:..|....|:|:.|:
Zfish   450 TFDKQSKEIDLNGGAFLPSCGRNVNSTVHNLMFSVITQAEGMINEIRTAFKGALDDLKWMDEQTR 514

  Fly   756 QLAEEKVNAMSLKIGYPDFILNPSELNSKYAGIEIYPEKYFENTLNVLLHTAKTEQAKLHERVNK 820
            |.|::|.:|:...||:|||||:..||:..|.|.|:..:.:|:|.:|....:|:....:|.:..|:
Zfish   515 QAAKDKADAIYDMIGFPDFILDSKELDDVYDGYEVTEDNFFQNMINFYNFSARVMADQLRKPPNR 579

  Fly   821 TNWQTAPAIVNAYYSRNKNQIMFPAGILQPPFYHRHFPKSLNFGGIGVVIGHELTHGFDDKGRLF 885
            ..|...|..|||||...||.|:|||||||.|||.:..||:|||||||||:||||||.|||:||.:
Zfish   580 DQWSMTPPTVNAYYMPTKNGIVFPAGILQAPFYAQDHPKALNFGGIGVVMGHELTHAFDDQGREY 644

  Fly   886 DRNGNIHKWWTDSSIRGFDERARCIIAQYSNYTVEEVGIVLNGESTQGENIADNGGLRQAFHAYQ 950
            |::||:..||.:||:..|..|..|::.||:.||:.  |..:||:.|.||||||||||:.|:|||:
Zfish   645 DKDGNLRSWWQNSSVEAFKNRTECMVDQYTQYTIN--GEHINGKQTLGENIADNGGLKAAYHAYR 707

  Fly   951 RWLKEHPSEVSDEILPGLNMTGPQLFFLNFGQVWCGAMRPEAIRNKLNTAIHSPGRFRVIGTLSN 1015
            .|::::..|   :.||.:|:|..||||:.|.||||....||:....|.|..|||.::||||||||
Zfish   708 SWVQKNGEE---KRLPAVNLTNDQLFFVGFAQVWCSVRTPESAHEGLMTDPHSPPKYRVIGTLSN 769

  Fly  1016 SVDFAREFNCPLGSPMNPQKKCSVW 1040
            |.:||..|.|||||.||...:|.||
Zfish   770 SPEFAEHFQCPLGSSMNSGHRCEVW 794

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep4	NP_650904.3	M13	274..1038	CDD:189000	275/794 (35%)
ece2b	XP_017206531.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170585576
Domainoid	1	1.000	45	1.000	Domainoid score	I12171
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG61902
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100162
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.860