Protein Alignment Nep4 and Nep5

DIOPT Version :9

• Sequence 1: NP_650904.3
• Gene: Nep4 / 42449
• FlyBaseID: FBgn0038818
• Length: 1040
• Species: Drosophila melanogaster
• Sequence 2: NP_733186.2
• Gene: Nep5 / 43255
• FlyBaseID: FBgn0039478
• Length: 882
• Species: Drosophila melanogaster
• Alignment Length: 863
• Identity: 233/863 - (26%)
• Similarity: 361/863 - (41%)
• Gaps: 218/863 - (25%)

  Fly   270 MDNKVDPCVDFYKYACGNWERLHPIPKDKAGFDTFEMLRESLDLVLRNLLEKNTPVHSAAELRKS 334
            ||.:.|||.|||::.||.|...||.|......|.|...:..:..|:|..|..|.
  Fly   146 MDEQTDPCEDFYQFTCGRWANEHPRPDSVTSNDWFRERQAHIMRVVREFLRSNI----------- 199

  Fly   335 PVRNTLFKLNEQGEGEGEADQAAELTAERLRRHIVSKRQLLNRVLVRYKRYTNGTKRKRLIETPR 399
                                                                             
  Fly   200 ----------------------------------------------------------------- 199

  Fly   400 ERTKEEEAAPPVVLPKDKTKDKSDNEEQLHVPTDFLKPHQDAQLKAKNLYRSCVNSAVLAKRGLE 464
              ||.|                                 .:|..|||.:||:|:::.:|.||.||
  Fly   200 --TKSE---------------------------------PEAVGKAKTMYRACMDTKLLDKRDLE 229

  Fly   465 PL-HTLIRELGGWPVLES--------------QWSESNFNW-QVLAATLRRYNNDILIVQWVGAD 513
            || :.|:|  .|.|||.|              :.:...:|| |.:.:..:....|::|    |.|
  Fly   230 PLINYLLR--FGLPVLPSALNLTLGSGSKYATEAANVKYNWLQSIVSIKQHLTMDLII----GFD 288

  Fly   514 IKNSEENIVQFDQTGLGLP---------------------TREYFLQPSN--------------- 542
            :.....|.. .::..||.|                     .:..|:|.|:
  Fly   289 VFPDPFNRT-INRIALGTPETDSAFPFNNDDSHKMLRKIHRKTIFMQNSDDEDDSEDDRESEEEE 352

  Fly   543 -AKY----LQAYQRYMAEVMHK---------------MGASKADAQ--RVASELVAFETQLAGIT 585
             ||.    :.||..|:.:|:.|               :|.::...|  |||.::..|:.:...:|
  Fly   353 AAKQTSTGMTAYLHYVRKVIEKYLLYVDPNVNQEEATLGITELVKQGVRVARKVHEFKEEAENMT 417

  Fly   586 APAEQRLNVTKLYKRMTLDQLQ-----AVVPEIK--WRAYLQSL-----QDREVLGTEEVVIYA- 637
            .|::   |.......:||..||     .:.|:..  |..|::.:     ....:..|:.:.|..
  Fly   418 KPSK---NPADDIVYITLQDLQNQTDKNIAPKTLPIWVRYMELILKGTRHAGNIQMTQNLTIITS 479

  Fly   638 ---VEYMSKLVTLLDETDPRTVSNYMMWRFVRHRINNVDDRFDDIKQSFYHALFGREESPQRWKV 699
               :.|:..:|..||:|....:.:|:....:...:.:.......:...:.....|.|.|..|...
  Fly   480 QADITYLQNIVEYLDDTPASHIESYLFLSTIEELVLHTSSSMRLLHSEYMRVAIGTEGSTPRSLY 544

  Fly   700 CIAQVNTNMGMAVGSMFVSRYFDNNSKRDTLRMTHDLQQAFRDILKTTDWLDDTTKQLAEEKVNA 764
            |...||:.:||||..:.....|.........||..|::::|..::|:|.|:|..||:...:|...
  Fly   545 CANGVNSLLGMAVSYVLADADFTKEKLPKVERMLSDIRRSFDRLVKSTSWMDAATKRKTIQKSAE 609

  Fly   765 MSLKIGYPDFILNPSELNSKYAGIEIYPEKYFENTLNVLLHTAKTEQAKLHERVNKTNWQTAPAI 829
            |...||:|.::.|.|.||:.|.|.|:....:.||.:: .:|....::....::.....|.|:|:.
  Fly   610 MKSFIGFPPWLRNASVLNAYYEGAEVNASTHLENLMD-FVHWQMMDKLNEMDKPEPIGWATSPSN 673

  Fly   830 VNAYYSRNKNQIMFPAGILQPPFYHRHFPKSLNFGGIGVVIGHELTHGFDDKGRLFDRNGNIHKW 894
            |||:::...|.|..|..|||.|||.... ::||:|.||.::||||||||||.||.|||.||:.:|
  Fly   674 VNAFHTFQSNAITVPIAILQYPFYDLGL-EALNYGSIGTILGHELTHGFDDSGRRFDRAGNMVEW 737

  Fly   895 WTDSSIRGFDERARCIIAQYSNYTVEEVGIVLNGESTQGENIADNGGLRQAFHAYQRWLKEHPSE 959
            |::.:|..:..|..|.:.|||.|.:.::...::||.|.|||||||||:|:||:||:.::||...|
  Fly   738 WSNRTIDEYVNRTECFVEQYSRYHLADIDEYIDGELTLGENIADNGGMREAFYAYRLYVKEVGRE 802

  Fly   960 VSDEILPGL-NMTGPQLFFLNFGQVWCGAMRPEAIRNKLNTAIHSPGRFRVIGTLSNSVDFAREF 1023
            .|.  |||| :.:..||||::||.:||....|.|.|..| |..|.||:.|:.|.||||.:|||.|
  Fly   803 RSK--LPGLEHYSHEQLFFISFGNLWCETYTPAASRYAL-TDSHCPGQMRLRGVLSNSEEFARTF 864

  Fly  1024 NCPLGSPMNP-QKKCSVW 1040
            .|..|:|||| |.||.:|
  Fly   865 KCARGTPMNPDQPKCRIW 882

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep4	NP_650904.3	M13	274..1038	CDD:189000	229/855 (27%)
Nep5	NP_733186.2	PepO	146..882	CDD:226118	232/861 (27%)
		M13	151..880	CDD:189000	229/854 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D157132at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.920