Protein Alignment Nep4 and Nepl11

DIOPT Version :9

• Sequence 1: NP_650904.3
• Gene: Nep4 / 42449
• FlyBaseID: FBgn0038818
• Length: 1040
• Species: Drosophila melanogaster
• Sequence 2: NP_649449.1
• Gene: Nepl11 / 40540
• FlyBaseID: FBgn0037230
• Length: 592
• Species: Drosophila melanogaster
• Alignment Length: 855
• Identity: 159/855 - (18%)
• Similarity: 277/855 - (32%)
• Gaps: 320/855 - (37%)

  Fly   238 ISEATAALQSFWNEEGTREGIR-----MTQAKTMKRYMDNKVDPCVDFYKYACGNWERLHPIPKD 297
            ||:|.|.|.......|..:.:|     ::.:..::.|:|....||.|||.|.|.
  Fly     2 ISKALAVLWIAGIAYGQDDLLRVETELLSFSHNLEPYLDTSKQPCQDFYGYVCS----------- 55

  Fly   298 KAGFDTFEMLRESLDLVLRNLLEKNTPVHSAAELRKSPVRNTLFKLNEQGEGEGEADQAAELTAE 362
                                        |||             .|:|.|
  Fly    56 ----------------------------HSA-------------NLSETG--------------- 64

  Fly   363 RLRRHIVSKRQLLNRVLVRYKRYTNGTKRKRLIETPRERTKEEEAAPPVVLPKDKTKDKSDNEEQ 427
                     ||....:|                       ||.:.|                  |
  Fly    65 ---------RQRFQSLL-----------------------KETDVA------------------Q 79

  Fly   428 LHVPTDFLKPHQDAQLKAKNLYRSCVNSAVLAKRGLEPL--HTLIRELGGWPVLE------SQWS 484
            |          .|.:|:..|.::||.:.     ||:|.|  ..|.|:.||||.||      ||.:
  Fly    80 L----------MDMELQLINFFKSCESG-----RGVEALKGSQLYRQSGGWPSLEPNKVNASQRT 129

  Fly   485 ESNFNWQVLAATLRRYNNDILIVQWVGADIKNSEENIVQFDQTGLGLPT--REYFLQPSNAK--Y 545
            .....|..|......          |||.         .|.:|.:.:.:  |...|||...:  .
  Fly   130 NQTQRWLGLLGYFHE----------VGAP---------YFFETSVTMQSNKRLVVLQPDGTRRNT 175

  Fly   546 LQAYQRYMAEVMHKMGASKADAQRVASELVAFETQLAGITAPAEQRLNVTKL------------- 597
            |:.:::.:.||:...|..::.|...|.|:::.|          ..|.::.|.
  Fly   176 LRKFEQRVGEVLQSFGIEQSRAHVTALEVLSLE----------RSRRDIVKADHVEDQVQFSYGN 230

  Fly   598 YKRMTLDQLQAVVPEIKWRAYLQSLQDREVLG------TEEVVIYAVEYMSKLVTLLDETDPRTV 656
            :||:.......:  .:.|..|.     |::||      ::.:|:..:..:.:...||..|   ::
  Fly   231 FKRIVFGNASLI--RLDWDGYF-----RKLLGGKTPQASDTIVVKQLPRLVEYFALLQNT---SM 285

  Fly   657 SNYMMWRFVRHRINNVDDRFDDIKQSFYHALFGREESPQRWKVCIAQVNTNMGMAVGSMFVSRYF 721
            ...:.|.:..:.::.||.....:.:::...|:..         .:.:|..|
  Fly   286 VRLLNWIWTDYLMDIVDADCHQLSETYAGDLYAH---------VVQRVTAN-------------- 327

  Fly   722 DNNSKRDTLRMTHDLQQAFRDILKTTDWLDDTTKQLAEEKV-NAM--------SLKIGYPDFILN 777
                :.:..:|..:|.:|:.|.|..:.|:|:.::|.:.:.: |.|        .|...|...:|.
  Fly   328 ----RVELAQMYSELGKAYTDQLGGSVWIDEISRQSSRQFLGNIMHTTLNGDERLDAAYHSILLG 388

  Fly   778 PSELNSKYAGIEIYPEKYFENTLNVLLHTAKTEQAKLHERVNKTNWQTAPAIVNAYYSRNKNQIM 842
            ...|   |..:|  ..:.|:.|..:..|:|        ::|.:.....||  |||:..::.
  Fly   389 RRSL---YRNLE--KLRKFQRTRRLASHSA--------QQVRRYAQMFAP--VNAFLGQHN---- 434

  Fly   843 FPAGILQPPFYHRHFPKSLNFGGIGVVIGHELTHGFDDKGRLFDRNGNIHKWWTDSSIRGFDERA 907
                 |..|         ||:    :::|...:......|......|   .|.:..|.|.|....
  Fly   435 -----LSTP---------LNY----LLLGEFFSRSLVAAGSSSRTQG---AWRSSDSERRFAIFQ 478

  Fly   908 RCIIAQYSNYTVEEVGIVLNGESTQGENIADNGGLRQAFHAYQRWLKEHPSEVS--DEILP--GL 968
            :|:..|     ...:.::|:       .:|.    |||..||.:||......|.  |.:|.  ..
  Fly   479 QCVGKQ-----TNAIDLLLS-------LLAQ----RQALSAYGQWLATQAGLVERVDAVLAAGSS 527

  Fly   969 NMTGPQLFFLNFGQVWC----GAMRPEAIRNKLNTAIHSPGRFRVIGTLSNSVDFAREFNCPLGS 1029
            .|:..:|||:....|.|    ||::.:..|.    ..|:        ||.||.:|...|.|..|.
  Fly   528 KMSLQRLFFVTSLLVDCRSELGALQQDRKRQ----VTHA--------TLRNSPEFLEAFRCRPGD 580

  Fly  1030 PMNPQ-KKCS 1038
            .:.|| ::|:
  Fly   581 VLYPQDQRCN 590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep4	NP_650904.3	M13	274..1038	CDD:189000	149/812 (18%)
Nepl11	NP_649449.1	GluZincin	45..589	CDD:301352	149/809 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910