Protein Alignment Nep4 and Nepl10

DIOPT Version :9

• Sequence 1: NP_650904.3
• Gene: Nep4 / 42449
• FlyBaseID: FBgn0038818
• Length: 1040
• Species: Drosophila melanogaster
• Sequence 2: NP_610787.1
• Gene: Nepl10 / 36366
• FlyBaseID: FBgn0033742
• Length: 633
• Species: Drosophila melanogaster
• Alignment Length: 834
• Identity: 165/834 - (19%)
• Similarity: 274/834 - (32%)
• Gaps: 289/834 - (34%)

  Fly   258 IRMTQAKTMKRYMDNKVDPCVDFYKYACGNWERLHPIPKDKAGFDTFEMLRESLDLVLRNLLEKN 322
            |.:..:..:...::....||.:|:.:|||.:......      .|.||.:.
  Fly    24 INVATSNDIHNNLNRTTSPCTNFWNFACGRFSSASKY------VDNFERVE-------------- 68

  Fly   323 TPVHSAAELRKSPVRNTLFKLNEQGEGEGEADQAAELTAERLRRHIVSKRQLLNRVLVRYKRYTN 387
                                           ||.|....|.:..|:.....|..|::.:.::|..
  Fly    69 -------------------------------DQFATAMVEFMESHLGENDTLAPRLIKQMRQYYK 102

  Fly   388 GTKR--KRLIETPRERTKEEEAAPPVVLPKDKTKDKSDNEEQLHVPTDFLKPHQDAQLKAKNLYR 450
            ..|.  ::|...||              |::..     |:..|| |..||            :|
  Fly   103 ACKEDTRKLHGNPR--------------PEELV-----NQWILH-PKKFL------------VY- 134

  Fly   451 SCVNSAVLAKRGLEPLHTLIRELGGWPVLESQWSESNFNWQVLAATLRRYNNDILIVQWVGADIK 515
                       ||                                      |.:.|.:.|.....
  Fly   135 -----------GL--------------------------------------NGVFIDERVDVAAN 150

  Fly   516 NSEENIVQFDQTGLGLPTREYFLQPSNAKYLQAYQRYMAEVMHKMGASKADAQRVASELVAFETQ 580
            :|...::|.....   |...|    |:.:.||..:.| .|..:.||
  Fly   151 DSMRWVIQLRMPD---PADRY----SDRRVLQLMRLY-EEAWYSMG------------------- 188

  Fly   581 LAGITAPAEQRLNVTKLYKRM--TLDQLQAVVPEIKWRAYLQSLQD--------REVLG---TEE 632
                         |.||.::|  ..|:.:|..|.:...::.:..|:        .|:||   |||
  Fly   189 -------------VVKLVEKMHQLQDKYRAEYPVVYTWSFSELRQEIPIPHSFFIELLGVNHTEE 240

  Fly   633 VV-----IYAVEYMSKLVTLLDE--TDPRTVSNYMMWRFVRHRINNVDDRFDDIKQSFYHALFGR 690
            :.     :..|||:.:....|.:  ::|:..       ::|.|      ::..:::|     ..|
  Fly   241 LYHLTFEVSDVEYLRECFRCLRDFASEPKDT-------YIRAR------QYVLVEES-----EPR 287

  Fly   691 EESPQRWKVCIAQVNTNMGMAVGSMFVSRYFDNNSKRDT---LRMTHDLQQAFRDILKTTDWLDD 752
            |.:|   :.||..:...:.:.:..:: .|:...|.:.||   |.:...|:.||...| ..:.|..
  Fly   288 ERNP---RSCIHHMRAYLPLGMNYIY-DRFIYQNREEDTSKVLEILSTLKAAFGQYL-DANRLQL 347

  Fly   753 TTKQLA--EEKVNAMSLKIGYPDFILNPSELNSKYAGIEIYPEKYFENTLNVLLHTAKTEQAKLH 815
            |..|||  ..|:..:.:|||......:|...|:.|.........:..|.|.......:.:.|.|.
  Fly   348 TPNQLAYVRAKLEGIQIKIGNLPEEKSPEFYNNHYGSANFSATNFLANLLEAFALRTRLQNAGLL 412

  Fly   816 ERVNK-------TNWQTAPAIVNAYYSRNKNQIMFPAGILQ-PPFYHRH---FPKSLNFGGIGVV 869
            .|.::       .|.....|..:.:|...:|.|..|...|| |.|.||.   |..||    :|.|
  Fly   413 ARNSRVDLRHYYVNDNVRKARTSPFYENERNTITVPMEFLQWPLFDHREHTIFQHSL----LGAV 473

  Fly   870 IGHELTHGFDDKGRLFDRNGNIHKWWTDSSI-------RGFDERARCIIAQYSNYTVEEVGIVLN 927
            :|||:.|.|:.:|.|||..||      :|.:       :.|.:..:|         .||...|
  Fly   474 LGHEMNHAFEQEGILFDAAGN------ESPVGLEIRESKPFRDAIKC---------AEEQPFV-- 521

  Fly   928 GESTQGENIADNGGLRQAFHAY------QRWLKEHPSEVSDEILPGLNMTGPQLFFLNFGQVWCG 986
               :..|.:||..||:.|:.|:      .|..:..|.....|      .|.||||.|::.|.:||
  Fly   522 ---SLKERLADLNGLQLAYDAFFGLAHDSRQFEYRPYAFEQE------FTAPQLFHLSYAQFFCG 577

  Fly   987 AMRPEAIRNKLNTAIHSPGRFRVIGTLSNSVDFAREFNCPLGSPMNPQKKCSVW 1040
            ::.|        ...|.....||..::.|...||.:|||    ..:|...|.:|
  Fly   578 SLPP--------VIAHDRDDERVNVSVGNLRQFAYDFNC----ETSPSSVCEMW 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep4	NP_650904.3	M13	274..1038	CDD:189000	162/814 (20%)
Nepl10	NP_610787.1	GluZincin	41..608	CDD:301352	159/800 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.920