Protein Alignment Nep4 and Nepl8

DIOPT Version :9

• Sequence 1: NP_650904.3
• Gene: Nep4 / 42449
• FlyBaseID: FBgn0038818
• Length: 1040
• Species: Drosophila melanogaster
• Sequence 2: NP_609795.2
• Gene: Nepl8 / 34983
• FlyBaseID: FBgn0032585
• Length: 619
• Species: Drosophila melanogaster
• Alignment Length: 812
• Identity: 155/812 - (19%)
• Similarity: 266/812 - (32%)
• Gaps: 264/812 - (32%)

  Fly   269 YMDNKVDPCVDFYKYACGNWERLHPIPKDKAGFDTFEMLRESLDLVLRNLLEKNTPVHSAAELRK 333
            ::|.:.:||.::|.:|||.:...|   .|...||..:||...::   :||:
  Fly    27 HVDKEANPCENYYNHACGQYNMRH---IDDTFFDIIQMLDHQVN---QNLV-------------- 71

  Fly   334 SPVRNTLFKLNEQGEGEGEADQAAELTAERLRRHIVSKRQLLNRVLVRYKRYTNGTKRKRLIETP 398
                                                                             
  Fly    72 ----------------------------------------------------------------- 71

  Fly   399 RERTKEEEAAPPVVLPKDKTKDKSDNEEQLHVPTDFLKPHQDAQLKAKNLYRSCVNSAVLAKRGL 463
                              |..|:.:...||   .||.....|.  |....|.||..    |.|.:
  Fly    72 ------------------KLMDELEMSSQL---PDFNVSSVDG--KVLRYYLSCRG----APRNM 109

  Fly   464 EPLHTLIRELG-----GWPVL---ESQWSESNFNWQVLAATLRRYN-NDILIVQWVGADIKNSEE 519
            :.|...::.:.     .||..   .|.|.:.||.|....|.|.||. .::.....|.::.:|:.|
  Fly   110 DSLSQYLKVISPGEGLTWPQFIPDGSSWPQENFKWLKALAHLHRYGLTNVFFNLEVVSNPRNASE 174

  Fly   520 NIVQFDQTGLG----LPTREYFLQPSNAKYLQAYQRYMAEVMHKMGASKADAQRVASELVAFETQ 580
            .:|:.:....|    ||..  |::             :..|::.:....::...:|.::...|..
  Fly   175 YMVELNTPTFGEESQLPNS--FIE-------------ILSVLYIIKVPSSEIITLARKMRTLELL 224

  Fly   581 LAGITAPAEQRLNVTKLYKRMTLDQLQAVVPEIKWRAYLQSLQDREVLGTEEVVIYAVEYMSKLV 645
            |..:..|.:...|     :.:::...|..... .|:.:.:.|.........:|::....|.:.|.
  Fly   225 LKTMINPIDTLNN-----RYISIRDFQMETGH-NWQRFFEILIGSSAAPELQVLVRNFRYFTALK 283

  Fly   646 TLLDETDPRTVSNYMMWRFVRHRINNVDDRFDDIKQSFYHALFGREESPQRWKVCIAQVNTNMGM 710
            .|:|:.|.|.|::|:|.||.   |..:|:           .:.|||.:.     |::||..||.:
  Fly   284 ELMDKQDARLVASYIMTRFA---IFLLDE-----------TMGGRESTE-----CVSQVRRNMNL 329

  Fly   711 AVGSMFVSRYFDNNSKRDTLRMTHDLQQAFR-DILKTTD--WLDDTTKQL------AEE-KVNAM 765
            |...::..|:|::::....:....|:.:..| ..|...|  .|:.|..|:      ||. ::|.:
  Fly   330 AANMLYKERFFEDSTFSANILEIKDIFEKLRHQFLLQVDQNHLELTALQMKFFVRKAEAIEINVV 394

  Fly   766 SLK--------IG--YPDFILNPSELNSKYAGIEIYPEKYFENTLNVL-LHTAK--TEQAKLH-E 816
            :|.        ||  |.|......||:            |.:..|.|| ..|.|  .:.:|.| |
  Fly   395 NLPKTDDLRHFIGQYYQDLQFPTGELD------------YHQEHLKVLQFRTQKMLAQSSKGHSE 447

  Fly   817 RVNKTNW--QTAPAIVNAYYSRNKNQIMFPAGILQP--PFYHRHFPKSLNFGGIGVVIGHELTHG 877
            ..|...:  |.||                    |.|  ||:.........:..:|.::.|.|...
  Fly   448 EQNILTYRSQAAP--------------------LPPPQPFFQLESEDVFKYSLMGYIMAHHLISA 492

  Fly   878 FDDKGRLFDRNGNIHKWWTDSSIRG--FDERARCIIAQYSNYTVEEVGIVLNGESTQGENIADNG 940
            |..:|.....:||      |.|.|.  |:|...|:.....|.               .|::.|..
  Fly   493 FATEGITIGSDGN------DQSFRSHRFEEAVSCLSRNSENI---------------DESMGDIA 536

  Fly   941 GLRQAFHAYQRWLKEHPSEVSDEILPGLNMTGPQLFFLNFGQVWCGAMRPEAIRNKLNTAIHSPG 1005
            ||..|:..|.:..|..      ..|...::...|:||||.||.:||        |......:...
  Fly   537 GLELAYFTYAKMAKNR------NRLDFTHLPPEQIFFLNVGQFFCG--------NSDMLVQYKED 587

  Fly  1006 RFRVIGTLSNSVDFAREFNCPLGSPMNPQKKC 1037
            :.|:...:.....|.:.|.|....|.:  :||
  Fly   588 QVRLQRAIEGFEPFDKAFGCYRNKPKH--EKC 617

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep4	NP_650904.3	M13	274..1038	CDD:189000	154/807 (19%)
Nepl8	NP_609795.2	GluZincin	32..618	CDD:301352	154/807 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454861
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840