Protein Alignment Nep4 and Nepl6

DIOPT Version :9

• Sequence 1: NP_650904.3
• Gene: Nep4 / 42449
• FlyBaseID: FBgn0038818
• Length: 1040
• Species: Drosophila melanogaster
• Sequence 2: NP_609023.3
• Gene: Nepl6 / 33893
• FlyBaseID: FBgn0259716
• Length: 655
• Species: Drosophila melanogaster
• Alignment Length: 675
• Identity: 160/675 - (23%)
• Similarity: 254/675 - (37%)
• Gaps: 178/675 - (26%)

  Fly   438 HQDAQ----------LKAKNLYRSCVNSAVLAKRGLEPLHTLIRELGG----WPVLESQ---WSE 485
            ||.:|          .|..:.||:| ..|..:.|.:|  |.|.....|    ||....:   |.:
  Fly    87 HQRSQSPGFNESSVEAKVLHFYRTC-REAPPSTRKME--HYLRLAPPGQALTWPQFMPRGEPWPK 148

  Fly   486 SNFNWQVLAATLRRYNNDILIVQWVGADIKNSEENIVQFDQTGLGLPTREYFLQPSNAKYLQAYQ 550
            :.|.|......|.||....::|..:   :..|.||..:| :..:.:|:.|
  Fly   149 AQFKWMKSLGHLYRYGFTNVLVNVL---VLRSSENSNRF-RLDISMPSLE--------------- 194

  Fly   551 RYMAEVMHKMGASKADAQRVASELVAFET-QLAGITAPAEQRLNVTKLYKRMTLDQLQAVVPEI- 613
                          .|||.:...|....| |:.|:  |.:..|.:.:..:|  |:....|:.|:
  Fly   195 --------------GDAQHLGGFLSTLATLQIIGV--PTKSILPLVRKIRR--LESAIRVLTEVD 241

  Fly   614 -------------------KWRAYLQSLQDREVLGTEEVVIYA--VEYMSKLVTLLDETDPRTVS 657
                               .|:.:::|:....|  :...|:.|  .:|.:.|..|:|.||...|:
  Fly   242 DDDESETWTLRQWEYKTGYAWQGFVESIVGHSV--SHHYVMQAQNAKYFTGLKRLMDSTDAEVVA 304

  Fly   658 NYMMWRFVRHRINNVDDRFDDIKQSFYHALFGREESPQRWKVCIAQVNTNMGMAVGSMFVSRYFD 722
            ||:|.|||.:.|::..|..:.|.                   |:..:..||.:|...::..|:.|
  Fly   305 NYIMTRFVLYLIDDFIDSNEHID-------------------CVTDMRRNMNLASNLLYKERFLD 350

  Fly   723 NNS-KRDTLRMTHDLQQAFRDILKTTDWLDDTTKQLAEEKVNAMSLKIGYPDFILNPSELN---- 782
            ..: ::.|..:|...:|..|..|..   :::....|..|:.:.::.|..:  .:||...|.
  Fly   351 PATLQQYTQEVTKVFEQLRRQFLLQ---INENRLGLTSEQNSMVATKAQH--VVLNIGNLPRGRD 410

  Fly   783 -----SKYAGIEIYP---EKYFENTLNVLLHTAKTEQAKLHERV-----------NKTNWQTAPA 828
                 |::....::|   ..|....||:|....:.:..:|::..           .||...:.|
  Fly   411 HRSFVSRHYEDLVFPLPDFDYAREHLNLLEFRTRKQVLQLNQSAPTPDEFFYLSDPKTAMSSGP- 474

  Fly   829 IVNAYYSRNKNQIMFPAGILQPPFY----HRHFPKSLNFGGIGVVIGHELTHGFDDKGRLFDRNG 889
                ||....|.|:.|.|:||.||:    |..|..||    :|.|:.|||.|..|..|..:||.|
  Fly   475 ----YYLMRLNIIVVPHGLLQEPFFAADSHDIFKYSL----LGFVLAHELMHSVDTVGLYYDRYG 531

  Fly   890 NIHKWWTD-SSIRGFDERARCIIAQYSNYTVEEVGIVLNGESTQ--GENIADNGGLRQAFHAYQR 951
            |||:.... ||...|....:|                ||..|||  .|.|||..||..|:..|
  Fly   532 NIHEIGPQISSSPRFVAGLQC----------------LNRNSTQYLDERIADIAGLDLAYSTY-- 578

  Fly   952 WLKEHPSEVSDEILPGLNMTGP-QLFFLNFGQVWCGAMRPEAIRNKLNTAIHSPGRFRVIGTLSN 1015
              .::.|::|   |.......| |:||||..|.:||...|      :|...|.....|:...|:.
  Fly   579 --FQNSSQMS---LTDFTTIPPQQIFFLNLAQFFCGDGDP------INFVGHDNDETRLQQMLNG 632

  Fly  1016 SVDFAREFNCPLGSPMNPQKKCSVW 1040
            ...|...|.||..|  |..:||.:|
  Fly   633 FAPFHEAFGCPAKS--NQPEKCQLW 655

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep4	NP_650904.3	M13	274..1038	CDD:189000	158/671 (24%)
Nepl6	NP_609023.3	M13	42..653	CDD:189000	158/671 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454859
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840