Protein Alignment Nep4 and Nepl4

DIOPT Version :9

• Sequence 1: NP_650904.3
• Gene: Nep4 / 42449
• FlyBaseID: FBgn0038818
• Length: 1040
• Species: Drosophila melanogaster
• Sequence 2: NP_609019.1
• Gene: Nepl4 / 33889
• FlyBaseID: FBgn0031805
• Length: 652
• Species: Drosophila melanogaster
• Alignment Length: 827
• Identity: 160/827 - (19%)
• Similarity: 271/827 - (32%)
• Gaps: 260/827 - (31%)

  Fly   258 IRMTQAKTMKRYMDNKVDPCVDFYKYACGNWERLHPIPKDKAGFDTFEMLRESLDLVLRNLLEKN 322
            |......|:..|:|::.:||.|||.||||.|...|      ....|..|:.||
  Fly    42 INQQHIDTLMSYVDSEKNPCEDFYAYACGKWRAKH------GSHTTATMISES------------ 88

  Fly   323 TPVHSAAELRKSPVRNTLFKLNEQGEGEGEADQAAELTAERLRRHIVSKRQLLNRVLVRYKRYTN 387
                               ::|.|.|         :|..:.||
  Fly    89 -------------------QINRQYE---------DLFLQLLR---------------------- 103

  Fly   388 GTKRKRLIETPRERTKEEEAAPPVVLPKDKTKDKSDNEEQLHVPTDFLKPHQDAQLKAKNL--YR 450
                             ..:||....|                            :.||.|  |:
  Fly   104 -----------------NPSAPEYGYP----------------------------MFAKVLAHYQ 123

  Fly   451 SCVNSAVLAKRGLEP-LHTLIRELGGWPVLESQWSESNFNWQVLAATLRRYNNDILIVQ----WV 510
            ||:   .|.|..|.. :..|.|:|..        |.::.:|..|.|.|.||......||    |.
  Fly   124 SCI---ALEKPDLRRYIELLDRDLLA--------SLNSTHWMHLLAALGRYGYHGHYVQVEVRWY 177

  Fly   511 GADIKNSEENIVQFDQTGLGLPTREYFLQPSNAKYLQAYQRYMAEVMHKMGASKADAQRVASELV 575
                 |:..:::              ||.|.|.....:..:.:.:.:.:.|:|.....::..:..
  Fly   178 -----NATHHMI--------------FLLPHNRHLNLSLTQDIYDALSQDGSSWPPLHQLQEQFR 223

  Fly   576 AFETQLAGITAPAEQRLNVTKLYKRMTLDQLQAVVPEIKWRAYLQSLQDREVLGTEEVVIYAVEY 640
            :.|..|..:..|.    :....::..:|||::..||.:.|...|::...|.|.|.....:..::.
  Fly   224 SLEQNLVRLAKPH----SADDTFRNYSLDQIRTEVPGLHWDEALRTQLGRSVPGNHVFQVDDLDA 284

  Fly   641 MSKLVTLLDETDPRTVSNYMMWRFVRHRINNVDDRFDDIKQSFYHALFGREESPQ--RWKVCIAQ 703
            :..||..|:..|...::.|.:.||:.|.:            ...|......||.|  |.:.||..
  Fly   285 IEGLVEYLNTVDTLLLNRYSLARFLSHLL------------ELPHNPLATWESGQRSRGRNCIRH 337

  Fly   704 VNTNMGMAVGSMFVSRYFDNNSKRD---------------TLRMTHDLQQAFRDILKTTDWLDDT 753
            :..::.:.:..::...::......|               .||:.|:.....:|::|:
  Fly   338 MRRSVYLPMNYVYERSFYSRRRHADELVIHSVFQQLQSQLELRVQHNAFNLSQDLVKS------- 395

  Fly   754 TKQLAEEKVNAMSLKIGYPDFILNPSELNSKY--------AGIEIYPEKYFENTLNVLL--HTAK 808
                .:.||:.|.:.:|.    |.|:.....|        .|.:.|     ||.||.||  :|..
  Fly   396 ----LQAKVHQMRINVGN----LPPNVTEQFYWDSDRRWSVGRDFY-----ENHLNSLLYYYTLV 447

  Fly   809 TEQAKLHERVNKTNWQT-------APAIVNA--YYSRNKNQIMFPAGILQPPFYHRHFPKSLNFG 864
            .:.....::..:..|.:       .|..::|  |:....|.|..|...::.||:..:|..:|.:|
  Fly   448 ADLESSSDQEERDIWYSFNMHTPEFPDNIDATPYFYCLGNIIFVPYSYVKRPFFDANFWPALLYG 512

  Fly   865 GIGVVIGHELTHGFDDKGRLFDRNGNIHKWWTDSSIRGFDERARCIIAQYSNYTVEEVGIVLNGE 929
            .:...:|||:.|.||.....:|..||         :|.|.::    :.:...|. ..||.:.:..
  Fly   513 DLANTLGHEIMHAFDTDLVDYDAQGN---------LRNFSDQ----LGEVELYN-GAVGCLNSSA 563

  Fly   930 STQGENIADNGGLRQAFHAY-QRWLKEHPSEVSDEILPGLNMTGPQLFFLNFGQVWCGAMRPEAI 993
            ....|..:|..|.|.|...| ..||....:              .:|:||.|...:||....:
  Fly   564 VMLNERTSDVSGSRLAMQTYGGDWLTRSGN--------------GRLYFLQFAHFFCGDEGDQ-- 612

  Fly   994 RNKLNTAIHSPGRFRVIGTLSNSVDFAREFNCPLGSPMNPQKKCSVW 1040
                   .|..|..|:...|.....||..|.|.:||.|....:|..|
  Fly   613 -------YHDSGSQRLNYALGQVPQFAEVFRCHVGSGMTSADQCPFW 652

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep4	NP_650904.3	M13	274..1038	CDD:189000	154/807 (19%)
Nepl4	NP_609019.1	PepO	51..643	CDD:226118	155/807 (19%)
		GluZincin	59..649	CDD:301352	154/805 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.920