Protein Alignment Nep4 and Kel

DIOPT Version :9

• Sequence 1: NP_650904.3
• Gene: Nep4 / 42449
• FlyBaseID: FBgn0038818
• Length: 1040
• Species: Drosophila melanogaster
• Sequence 2: NP_001178540.1
• Gene: Kel / 297025
• RGDID: 1565470
• Length: 713
• Species: Rattus norvegicus
• Alignment Length: 611
• Identity: 164/611 - (26%)
• Similarity: 294/611 - (48%)
• Gaps: 29/611 - (4%)

  Fly   439 QDAQLKAKNLYRSCVNSAVLAKRGLEPLHTLIRELGGWPVLESQWSESNFNWQVLAATLRRYNND 503
            :..:.||...|.||:::..:...|..||..:|:|||||.: ...|:..:|| |.|...:.:|.:.
  Rat   123 ESGEEKAFQFYNSCMDTDAIEASGTGPLVQIIKELGGWNI-SGNWTFFDFN-QNLRLLMSQYGHF 185

  Fly   504 ILIVQWVGADIKNSEENIVQFDQTGLGLPTREYFLQPSNAKYLQAYQRYMAEVMHKMGASKADAQ 568
            .....::..........|:|.||....:..::...|...|:.|:.|..|:..:...:|::..:||
  Rat   186 PFFRAYLHPHPAPPHTPIIQIDQPEFDILLQQDQEQKVYAQILREYVTYLNRLGTLLGSNPQEAQ 250

  Fly   569 RVASELVAFETQLAGITAPAEQRLNVTKLYKRMTLDQLQAVVPEIKWRAYLQSLQDREVLGTEEV 633
            :.||..:.|.::|.....|.:|:....||:..:|:|.||.:.|.|.|.:.||::.....|...:.
  Rat   251 QHASWSIVFTSRLFQFLRPQQQQQAQDKLFHVVTIDALQEMAPAIDWLSCLQAIFTPMSLSPSQT 315

  Fly   634 V-IYAVEYMSKLVTLLDE---TDPRTVSNYMMWRFVRHRINNVDDRFDDIKQSFYHALFGREESP 694
            : ::.::|:..:..|::|   .....:.:||:...|......:..:|.:.::.....|...:|.|
  Rat   316 LQVHDLDYLRNMSQLVEEGLLNHSEIIQSYMILGLVDTLSPALATKFQEARRELTQKLRKLKERP 380

  Fly   695 -----QRWKVCIAQVNTNMGMAVGSMFVSRYFDNNSKRDTLRMTHDLQQAFRDILKTTDWLDDTT 754
                 .||..|:.|..:.....:.::||...|..:.:...:.:..:::.|....||...|:.:.|
  Rat   381 PLPAYPRWMKCVEQTGSFFEPTLAALFVHEAFGPSIRSAAMELFAEIKDAVIVRLKKLSWISEET 445

  Fly   755 KQLAEEKVNAMSLKIGYPDFILNPSELNSKYAGIEIYPEKYFENTLNVLLHTAKTEQAKLHERVN 819
            ::.|..|:..:.:::|.|...|.......:|:.|::.| .:.::.|:.:......:.....:...
  Rat   446 RKEALNKLTQLQVEMGAPKRALKTEMAKQEYSDIQLGP-SFLQSFLSCVRSLQGRKVRSFLQPFP 509

  Fly   820 KTNWQTAPAIVNAYYSRNKNQIMFPAGILQPPFYHRHFPKSLNFGGIGVVIGHELTHGFDDKGRL 884
            ...||.:|..|:||||...:.::||||:|||||:|..:|:::|||.:|.::.|:|.|.|..
  Rat   510 YHRWQKSPWSVSAYYSVPDHVVVFPAGLLQPPFFHPGYPRAVNFGAVGSIMAHKLLHIFFQ---- 570

  Fly   885 FDRNGNIHKWWTDSSIRGFDERARCIIAQYSNYTVEEVGIVLNGESTQGENIADNGGLRQAFHAY 949
            |...|......|    |...|...|:..:|:.:.:..:. ..||..|..||.||.||:..||.||
  Rat   571 FLLPGGCPACDT----RALQEALLCLEHRYAAFPLPSMS-SFNGSHTLLENAADIGGVAIAFQAY 630

  Fly   950 QRWLKEHPSEVSDEILPGLNMTGPQLFFLNFGQVWCGAMRPEAIRNKLNTAIHSPGRFRVIGTLS 1014
            ::.:.|...|::   ||...::..||||.::.||.|   |....::..:|  |||.|.||.|.||
  Rat   631 RKRITERTGELT---LPNQELSPYQLFFRSYAQVMC---RELISQDPQDT--HSPPRLRVHGPLS 687

  Fly  1015 NSVDFAREFNCPLGSPMNPQKKCSVW 1040
            ||.|||:.|.||.||.:||..:|.:|
  Rat   688 NSPDFAKHFLCPSGSLLNPSTRCKLW 713

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep4	NP_650904.3	M13	274..1038	CDD:189000	162/607 (27%)
Kel	NP_001178540.1	PepO	75..713	CDD:226118	163/609 (27%)
		M13	78..711	CDD:189000	162/607 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166344517
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.850