Protein Alignment Nep4 and nep-24

DIOPT Version :9

• Sequence 1: NP_650904.3
• Gene: Nep4 / 42449
• FlyBaseID: FBgn0038818
• Length: 1040
• Species: Drosophila melanogaster
• Sequence 2: NP_503005.3
• Gene: nep-24 / 190993
• WormBaseID: WBGene00013786
• Length: 567
• Species: Caenorhabditis elegans
• Alignment Length: 727
• Identity: 135/727 - (18%)
• Similarity: 259/727 - (35%)
• Gaps: 227/727 - (31%)

  Fly   234 ASAEISEATAALQSFWNEEGTREGIRMTQAKTMKRYMDNKVDPCVDFYKYACGNWERLHPIPKDK 298
            |...|...|.|.::..|....     :|.|..:..|.|..||||.:|:::|||. |..|
 Worm    23 APLAIGATTPATRNVCNTPAC-----ITLAHMLHNYHDPSVDPCDNFHQFACGR-EHEH------ 75

  Fly   299 AGFDTFEMLRESLDLVLRNLLEKNTPVHSAAELRKSPVRNTLFKLNEQGEGEGEADQAAELTAER 363
                      |:.|:..:
 Worm    76 ----------ETEDIYTK----------------------------------------------- 83

  Fly   364 LRRHIVSKRQLLNRVLVRYKRYTNGTKRKRLIETPRERTKEEEAAPPVVLPKDKT-KDKSDNEEQ 427
                   |.:.:|.::.|:                              |.|::| :.||:|
 Worm    84 -------KTKTINNIMKRF------------------------------LKKNETSRSKSEN--- 108

  Fly   428 LHVPTDFLKPHQDAQLKAKNLYRSC----VNSAVLAKRGLEPLHTLIRELGGWPVLESQWSESNF 488
                            ..:.||::|    .||.....:.|:.:...|:.:|.|||::.:|.||.|
 Worm   109 ----------------AMRTLYKACKTLEKNSTASRNKALQDIFQDIQSIGAWPVVDDKWDESKF 157

  Fly   489 NWQVLAATLRRYNNDILIVQWVGADIKNSEENIVQFDQTGLGL-------PTREYFLQPSNA-KY 545
            :.           ||.|:             |:|:..:...||       ..|.:.:.|..| ::
 Worm   158 DL-----------NDFLV-------------NLVRLGRKNFGLFQMARYVNVRNFAIGPEAAWRH 198

  Fly   546 LQAYQRYMAEVMHKMGASKADAQRVASELVAFETQLAGITAPAEQRLNVTKLYKRMTLDQLQA-- 608
            .....:.::|:: |..:.:.:.:::..:|..:              :|:.|...:...:.:|.
 Worm   199 NVDLGKTISEIL-KANSVQTNNKKLLDDLAEY--------------VNLEKALSQHKFNTVQPGY 248

  Fly   609 -------VVPEIKW-RAYLQSLQ-DREVLGTEEVVIYAVEYM----------SKLVTLLDETDPR 654
                   .|..:.: |..|:.:. |:..|..|   :|.:.|:          :.|.|::..|..|
 Worm   249 IFSERSDFVSSVNFSRLVLEMMSPDKRTLFPE---VYQIMYLTNTSLFFGKNNNLETIIRNTSKR 310

  Fly   655 TVSNYMMWRFVRHRINNVDDRFDDIKQSFYHALFGREESPQRWKVCIAQVNTNMGMAVGSMFVSR 719
            .::||::::|       :|....|:       .:|   ||..:  |..:|...:..|....|...
 Worm   311 ALANYLIFKF-------IDTSIADL-------TYG---SPSAF--CEQKVINFLPRAALRAFYRN 356

  Fly   720 YFDNNSKRDTLRMTHDLQQAFRDILKTTDWLDDTTKQLAEEKVNAMSLKIGYPDFILNPSELNSK 784
            :....:::...::|...|.....|:..|||:...:|::|.::|::|::.|||||:...|.:|:..
 Worm   357 FISKENRKKITKLTEATQVQLLKIIGATDWMSIKSKKIAMDRVSSMNMVIGYPDYFDPPGKLDGL 421

  Fly   785 YAGIEI-YPEKYFENTLNVLLHTAKTEQAKLHERVNKTNWQTAPAIV-NAYYSRNKNQIMFPAGI 847
            :..:.: ..:.|:  |:...::....||...:.......:...|.:: ||.|:.|.|.:|..|..
 Worm   422 FEHLNLSSSDTYY--TVVRKINRFMREQEMDYYTGEVPYYPLFPGLMTNAMYNANDNNLMIFAPF 484

  Fly   848 LQPPFYHRHFPKSLNFGGIGVVIGHELTHGFDDKGRLFD-RNGNIHKWWTDSSIRGFDERARCII 911
            ...||:...||...|.......:.||:.|.|..  .|.| ..|....|.|......:::|.:|:.
 Worm   485 FDDPFFDSSFPDYANIAFTSNTLAHEMGHTFSP--HLMDIMTGTTEVWLTPKETEEYEKRVKCLE 547

  Fly   912 AQYSNYTVEEVG 923
            .||:.|...|.|
 Worm   548 DQYTEYDDPEYG 559

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep4	NP_650904.3	M13	274..1038	CDD:189000	126/687 (18%)
nep-24	NP_503005.3	GluZincin	58..561	CDD:301352	126/687 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161784
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.850