Protein Alignment Nep4 and nep-18

DIOPT Version :9

• Sequence 1: NP_650904.3
• Gene: Nep4 / 42449
• FlyBaseID: FBgn0038818
• Length: 1040
• Species: Drosophila melanogaster
• Sequence 2: NP_494297.1
• Gene: nep-18 / 186911
• WormBaseID: WBGene00019343
• Length: 701
• Species: Caenorhabditis elegans
• Alignment Length: 831
• Identity: 179/831 - (21%)
• Similarity: 303/831 - (36%)
• Gaps: 224/831 - (26%)

  Fly   266 MKRYMDNKVDPCVDFYKYACGNWERLHPIPKDKAGFDTFEMLRESLDLVLRNLLEKNTPVHSAAE 330
            :|.|.:..||||.||:::.||.:.. |.:..:..|:
 Worm    39 IKNYQNASVDPCEDFFEHTCGRYSE-HVMDDNSWGY----------------------------- 73

  Fly   331 LRKSPVRNTLFKLNEQGEGEGEADQAAELTAERLRRHIVSKRQLLNRVLVRYKRYTNGTKRKRLI 395
                                                  |..:|||.:|.. ..|.||
 Worm    74 --------------------------------------VQYKQLLYQVFA-IARKTN-------- 91

  Fly   396 ETPRERTKEEEAAPPVVLPKDKTKDKSDNEEQLHVPTDFLKPHQDAQLKAKNLYRSCVNSAVLAK 460
                                   |..|...|||.:.|                 :||::...:.:
 Worm    92 -----------------------KFNSKPNEQLRIFT-----------------KSCLDRKEMDE 116

  Fly   461 RGLEPLHTLIRELGGWPVLESQWSESNFNWQVLAA---TLRRYNNDILIVQWVGADIKNSEENIV 522
            ...:.|...|.|.||:|:::..|:|..|:...:.|   ::.|.....|.|:...|...|...|
 Worm   117 DTFQDLRNDIEERGGFPMIDPNWNEEKFDLSDMLAKYLSINRNRMGFLSVEPYAAIEGNKSVN-- 179

  Fly   523 QFDQTGLGLPTREYFLQPSN------AKYLQAYQRYMAEVMHKM------GASKADAQRVASELV 575
                        ..::.|..      |..:..|:..:|.::.::      ..::....:..:|||
 Worm   180 ------------RLYVSPGPHWVYNWAMGISIYKDSVAFMLRRLLKLENRELNETIYDKEFAELV 232

  Fly   576 AFETQLAGITAPAEQRLNVTKLYKRMTLDQLQAVVPEIKWRAYLQSL-------QDREVLGTEEV 633
            ..|...:.:.......|:...:.|...|..|..::|||.|...|::|       :|.|.| .|.|
 Worm   233 QLEANFSTLADYRNLALDNDNMSKSRNLTDLVKMIPEIDWIKILKALARHGTSEEDEEKL-LERV 296

  Fly   634 VIY-AVEYM----SKLVTLLDETDPRTVSNYMMWRFVRHRINNVDDRFDDIKQSFYHALFGREES 693
            .:: |.||.    .:|..:..||....::||::   ||..|        |:...||.     ::.
 Worm   297 TVHGAGEYFFGENRELARIATETPKSALANYLV---VRQLI--------DVALYFYD-----KDQ 345

  Fly   694 PQRWK---------VCIAQVNTNMGMAVGSMFVSRYFDNNSKRDTLRMTHD----LQQAFRDILK 745
            |::.|         .|..||.:...|...::|:.   .:..|.:.|::..:    ::..:..|..
 Worm   346 PRQNKFYNHVDQQSFCATQVASFFPMPSMNVFIE---SSQFKIENLKVIEEMFVKIKAEYEQIFT 407

  Fly   746 TTDWLDDTTKQLAEEKVNAMSLKIGYPDFILNPSELNSKYAGI---------EIYPE---KYFEN 798
            ..::|:...::....|:||:..|.|...:......|...|..:         ::|.:   .:.|.
 Worm   408 ENEYLELEIREFLIRKLNAIDGKFGLDQYTEGKPLLEKMYETLNFLDTDSPWQVYMKMWRHWSEQ 472

  Fly   799 TLNVLLHTAKTEQAKLHERVNKTNWQTAPAIVNAYYSRNKNQIMFPAGILQPPFYHRHFPKSLNF 863
            .:..::|....:...|........:|..|   |.:|      |..|  .|..|:....||.:.|:
 Worm   473 LVEHIVHDTPLDPVNLKMFGTHAAYQPYP---NHFY------INLP--YLTYPWMDADFPANTNY 526

  Fly   864 GGIGVVIGHELTHGFDDKGRLFDRNGNIHKWW---TDSSIRGFDERARCIIAQYSNYTVEEVGIV 925
            |.:|.|||||:.|.||...|..|.:|...::|   |:||...::.|.:|:..|||.|........
 Worm   527 GYLGYVIGHEIGHAFDHFHRKLDESGRQQQYWFTETNSSNTEYELREKCLRDQYSAYKEPGYDFF 591

  Fly   926 LNGESTQGENIADNGGLRQAFHAYQRWLKEHPSEVSDEI-LPGLNMTGPQLFFLNFGQVWCGAMR 989
            :||...:.|...|:.|:|.||..:::..||      |.. ||||.|:..||||.|:....|....
 Worm   592 MNGTHCRYEIAGDHMGIRTAFRVFEKVKKE------DRFRLPGLEMSEEQLFFYNYAFRQCDVYN 650

  Fly   990 PEAIRNKLNTAIHSPGRFRVIGTLSNSVDFAREFNCPLGSPMNPQKKCSVW 1040
            |..:...:....|...|:||.|.:.|..:||..||||..|||||:.||.::
 Worm   651 PNKLPRNMLARQHPTNRYRVNGVIQNIPEFAEAFNCPKNSPMNPEMKCKLY 701

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep4	NP_650904.3	M13	274..1038	CDD:189000	176/819 (21%)
nep-18	NP_494297.1	PepO	42..692	CDD:226118	172/817 (21%)
		M13	47..699	CDD:189000	176/819 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920