Protein Alignment Nep4 and nep-13

DIOPT Version :9

• Sequence 1: NP_650904.3
• Gene: Nep4 / 42449
• FlyBaseID: FBgn0038818
• Length: 1040
• Species: Drosophila melanogaster
• Sequence 2: NP_001342017.1
• Gene: nep-13 / 173672
• WormBaseID: WBGene00018196
• Length: 732
• Species: Caenorhabditis elegans
• Alignment Length: 867
• Identity: 168/867 - (19%)
• Similarity: 315/867 - (36%)
• Gaps: 250/867 - (28%)

  Fly   238 ISEATAALQSFWNEEGTREGI----------------RMTQAKTMKRYMDNKVDPCVDFYKYACG 286
            |:....|:..||..:...:.|                .:|.:.|:..:.:..:|||.|||:|:||
 Worm    52 IAICMGAVIVFWRMDSAPQAICKTDHNKTRDVCKTAECITLSSTLLNWQNTNIDPCEDFYEYSCG 116

  Fly   287 NWERLHPIPKDKAGFDTFEMLRESLDLVLRNLLEKNTPVHSAAELRKSPVRNTLFKLNEQGEGEG 351
            .::. |.:                                           |...:.||:
 Worm   117 RYQE-HTL-------------------------------------------NDGIRANEK----- 132

  Fly   352 EADQAAELTAERLRRHIVSKRQLLNRVLVRYKRYTNGTKRKRLIETPRERTKEEEAAPPVVLPKD 416
                  :....:|.|..|.|.|                          ..|...|.|..::..|.
 Worm   133 ------DTIVMKLIRQFVLKNQ--------------------------STTSNSENALMLLYEKC 165

  Fly   417 KTKDKSDNEEQLHVPTDFLKPHQDAQLKAKNLYRSCVNSAVLAKRGLEPLHTLIRELGGWPVLES 481
            ..:.:.:|.            ||:.::..:.::.:                  ||::|.||:.:.
 Worm   166 SLRYRMENR------------HQETEVIQREVFEN------------------IRKIGSWPIADK 200

  Fly   482 QWSESNFNWQVLAATLRRYNNDILIVQWVGADIKNSEENIVQFDQTGLGL-PTREYFLQPSNAKY 545
            .|:.|:||                        :.|...|:........|| .||...|.|.|.
 Worm   201 NWNSSHFN------------------------LNNMLSNMASIHMLPFGLFETRVIELYPMNT-- 239

  Fly   546 LQAYQRYMAEVMHKMGASKADAQRVASELVAFETQLAGITAPAEQ----------------RLNV 594
             .|.|..:.....|....:.:..|...:|::    :.|||:..::                .:::
 Worm   240 -TAKQLVIRPTKLKFSIPQEELVRAIRDLLS----VNGITSIMKKVKEDVAESFALDKEIGNIHI 299

  Fly   595 TKLYKRMTLDQLQAVVPEIKWRAYLQSLQDREV-----LGTEEVVIYAVEY------MSKLVTLL 648
            ....|..||.:||..||:|.:...::|..:.:.     |.|:   |::..:      .:.|.:::
 Worm   300 DPQPKPATLSELQKAVPDIDFERIIKSYLNPKTGNWSSLRTK---IFSARFELFFGKNNNLSSII 361

  Fly   649 DETDPRTVSNYMMWRFVRHRINNVDDRFDDIKQSFYHALFGREESPQRWKVCIAQVNTNMGMAVG 713
            ..|.||.::||:..:::.:.....   ||:.|      :|..::      .|...|.|::..|..
 Worm   362 ARTKPRILANYLFLKYIEYAYFFF---FDNTK------VFSDDD------FCTEVVTTSLPRASL 411

  Fly   714 SMFVSRYFDNNSKRDTLRMTHDLQQAFRDILKTTDWLDDTTKQLAEEKVNAMSLKIGYPDFILNP 778
            .:||..:|...:......:...::.|:.:|:..:.||.::|::.|.|||..|...|||.:.....
 Worm   412 RVFVRNHFKKENMAVASEIVEVVKTAYVEIINNSTWLHNSTRESAIEKVVKMKKVIGYTEEYERT 476

  Fly   779 SELNSKYAGIEI-YPEKYFENTLNVLLHTAKTEQAKLHERVNKTNWQT-----APAIV-NAYYSR 836
            ..|:..:..::: ..:.:|     ||:  .|..:.|:.:.::..:..:     .|.:: ||:|..
 Worm   477 GALDEMFETLQLSRSDSFF-----VLM--TKVNRFKIEQLMDFVSSDSLLNPIEPLVMANAFYFP 534

  Fly   837 NKNQIMFPAGILQPPFYHRHFPKSLNFGGIGVVIGHELTHGFDDKGRLFDRNGNIHKWWTDSSIR 901
            .||.:......|..|.:...:|:.:...|:|.|:.||:.|.||..||..|..|....|||.....
 Worm   535 TKNLLNVLVPFLDKPLFDFKYPRYVAMAGVGRVLAHEIGHAFDINGRQTDEIGRTRDWWTREDTE 599

  Fly   902 GFDERARCIIAQYSNYTVEEVGIVLNGESTQGENIADNGGLRQAFHAYQRWLKEHPSEVSDEILP 966
            .:|.|:.|...|::|:.........||.....|.|||..|:..::.|:::
 Worm   600 EYDRRSECFAEQFTNFKDPSFKGKQNGTEVLAEIIADALGMEASWIAFKK--------------- 649

  Fly   967 GLNMTGPQ------------LFFLNFGQVWCGAMRPEAIRNKLNTAI-HSPGRFRVIGTLSNSVD 1018
             :|:|..|            |:|......:|.   |..|..:.:..: |...:||:.|..|||..
 Worm   650 -INLTEEQGLIQFEDHDFGKLYFQVAALDFCA---PSRIEERYSDQLSHPTNKFRINGAFSNSRA 710

  Fly  1019 FAREFNCPLGSPMNPQKKCSVW 1040
            ||..:.||:||.|||.::|.::
 Worm   711 FADTYKCPVGSKMNPVQRCDMF 732

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep4	NP_650904.3	M13	274..1038	CDD:189000	160/811 (20%)
nep-13	NP_001342017.1	M13	104..729	CDD:189000	160/810 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161778
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.850